Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EED | O75530 | 20/20 | 1.00 |
| ▸ | RBBP4 | Q09028 | 20/20 | 1.00 |
| ▸ | SUZ12 | Q15022 | 20/20 | 1.00 |
| ▸ | EZH2 | Q15910 | 20/20 | 1.00 |
| ▸ | AEBP2 | Q6ZN18 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21113268 | 0.92 | EED (1.00) | EEDRBBP4SUZ12EZH2AEBP2 | |
| SCHEMBL28886574 | 0.91 | EED (0.84) | EEDRBBP4SUZ12EZH2AEBP2 | |
| SCHEMBL21113234 | 0.90 | EED (0.81) | EEDRBBP4SUZ12EZH2AEBP2 | |
| SCHEMBL21113311 | 0.89 | EED (0.80) | EEDRBBP4SUZ12EZH2AEBP2 | |
| SCHEMBL19964657 | 0.88 | EED (0.78) | EEDRBBP4SUZ12EZH2AEBP2 | |
| SCHEMBL21113213 | 0.86 | EED (0.86) | EEDRBBP4SUZ12EZH2AEBP2 | |
| SCHEMBL21113361 | 0.86 | EED (0.75) | EEDRBBP4SUZ12EZH2AEBP2 | |
| SCHEMBL28958915 | 0.83 | EED (0.83) | EEDRBBP4SUZ12EZH2AEBP2 | |
| SCHEMBL21113106 | 0.82 | EED (0.81) | EEDRBBP4SUZ12EZH2AEBP2 | |
| SCHEMBL21113220 | 0.81 | EED (0.79) | EEDRBBP4SUZ12EZH2AEBP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10968215-B2 | Pyrido five-element aromatic ring compound, preparation method therefor and use thereof | SHANGHAI HAIHE PHARMACEUTICAL CO., LTD. (CN) | 2021-04-06 | — | — | US | disclosed |
| US-10968215-B2 | Pyrido five-element aromatic ring compound, preparation method therefor and use thereof | SHANGHAI HAIHE PHARMACEUTICAL CO., LTD. (CN) | 2021-04-06 | — | — | US | disclosed |
| EP-3524602-A1 | PYRIDO FIVE-ELEMENT AROMATIC RING COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | Shanghai Haihe Pharmaceutical Co., Ltd. (CN) | 2019-08-14 | — | — | EP | disclosed |
| US-20190211010-A1 | PYRIDO FIVE-ELEMENT AROMATIC RING COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | HAIHE BIOPHARMA CO. LTD. (CN) | 2019-07-11 | — | — | US | disclosed |
| US-20190211010-A1 | PYRIDO FIVE-ELEMENT AROMATIC RING COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | HAIHE BIOPHARMA CO. LTD. (CN) | 2019-07-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10968215-B2 | Pyrido five-element aromatic ring compound, preparation method therefor and use thereof | EZH2, IKZF2, SUZ12 | EED 41/4885RBBP4 288/4885SUZ12 3/4885 |
| US-20190211010-A1 | PYRIDO FIVE-ELEMENT AROMATIC RING COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | EZH2, IKZF2, SUZ12 | EED 41/4885RBBP4 288/4885SUZ12 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.