Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 6/20 | 0.33 |
| ▸ | CNR2 | P34972 | 6/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.32 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.32 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.31 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21097890 | 0.94 | TSHR (0.33) | TSHRCYP2C9CA1CA2RAB9A | |
| SCHEMBL21232226 | 0.93 | TSHR (0.33) | TSHRCYP2C9CNR1CNR2CA1 | |
| SCHEMBL24001431 | 0.91 | TSHR (0.34) | TSHRCYP2C9CA1CA2RAB9A | |
| SCHEMBL21115557 | 0.90 | TSHR (0.33) | TSHRCYP2C9CNR1CNR2RAB9A | |
| SCHEMBL22540620 | 0.90 | TSHR (0.33) | TSHRCYP2C9CNR1CNR2RAB9A | |
| SCHEMBL17070487 | 0.90 | TSHR (0.34) | TSHRCYP2C9CNR1CNR2CA1 | |
| SCHEMBL19796600 | 0.90 | TSHR (0.37) | TSHRCYP2C9CNR1CNR2CA1 | |
| SCHEMBL21231959 | 0.89 | FFAR4 (0.32) | CYP2C9 | |
| SCHEMBL20171727 | 0.89 | TSHR (0.38) | TSHRCNR1CNR2CA1CA2 | |
| SCHEMBL20171701 | 0.89 | TSHR (0.38) | TSHRCNR1CNR2CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3502209-B1 | LIQUID-CRYSTALLINE MEDIA HAVING HOMEOTROPIC ALIGNMENT | MERCK PATENT GMBH (DE) | 2020-10-14 | — | — | EP | disclosed |
| EP-3502209-A1 | LIQUID-CRYSTALLINE MEDIA HAVING HOMEOTROPIC ALIGNMENT | Merck Patent GmbH (DE) | 2019-06-26 | — | — | EP | disclosed |