SCHEMBL21115838

SCHEMBL21115838

CCCCCC1CCC(c2ccc(-c3ccc(-c4ccc(OCC(C)(CO)CO)c(CCOC(=O)C(C)C)c4)c(CC)c3)c(F)c2)CC1

nearest known ligand 0.34

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
PPARD Q03181 4/20 0.34
FFAR4 Q5NUL3 3/20 0.33
CYP3A4 P08684 1/20 0.32
CYP2C9 P11712 1/20 0.32
APP P05067 1/20 0.32
S1PR1 P21453 2/20 0.31
S1PR3 Q99500 2/20 0.31
PPARG P37231 1/20 0.31
PPARA Q07869 1/20 0.31
FASN P49327 1/20 0.31
RARB P10826 1/20 0.30
DGAT1 O75907 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21115990 0.92 PPARD (0.34) PPARDFFAR4CYP3A4CYP2C9APP
SCHEMBL21115841 0.91 PPARD (0.33) PPARDFFAR4CYP3A4CYP2C9
SCHEMBL21115649 0.88 PPARD (0.33) PPARDFFAR4CYP3A4CYP2C9
SCHEMBL21115769 0.87 PPARD (0.31) PPARDFFAR4
SCHEMBL22540649 0.86 PPARG (0.33) PPARDCYP2C9PPARGPPARA
SCHEMBL21115839 0.85 SRD5A2 (0.32) FFAR4CYP2C9
SCHEMBL21231988 0.84 PPARD (0.32) PPARDFFAR4CYP3A4CYP2C9S1PR1
SCHEMBL21115594 0.83 FFAR4 (0.32) FFAR4
SCHEMBL21115989 0.83 PPARD (0.33) PPARDFFAR4S1PR1S1PR3
SCHEMBL21115625 0.83 PPARD (0.30) PPARDFFAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3502209-A1 LIQUID-CRYSTALLINE MEDIA HAVING HOMEOTROPIC ALIGNMENT Merck Patent GmbH (DE) 2019-06-26 EP disclosed