Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 4/20 | 0.39 |
| ▸ | BACE1 | P56817 | 3/20 | 0.39 |
| ▸ | STS | P08842 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22625244 | 0.90 | MAOB (0.43) | MAOBMAOANPC1RAB9AKDM4E | |
| SCHEMBL24595681 | 0.89 | MAOB (0.40) | MAOBMAOANPC1RAB9AKDM4E | |
| SCHEMBL24595657 | 0.88 | MAOB (0.39) | MAOBMAOANPC1RAB9AKDM4E | |
| SCHEMBL18535599 | 0.86 | MAOB (0.43) | MAOBMAOANPC1RAB9AKDM4E | |
| SCHEMBL22568818 | 0.85 | GLA (0.45) | MAOBMAOANPC1RAB9AKDM4E | |
| SCHEMBL21065622 | 0.83 | MAOB (0.47) | MAOBMAOANPC1RAB9AKDM4E | |
| SCHEMBL22624994 | 0.83 | MAOB (0.41) | MAOBMAOANPC1RAB9AKDM4E | |
| SCHEMBL21524227 | 0.82 | KDM4E (0.40) | MAOBMAOANPC1RAB9AKDM4E | |
| SCHEMBL23316742 | 0.82 | MAOB (0.44) | MAOBMAOANPC1RAB9AKDM4E | |
| SCHEMBL23713512 | 0.82 | NPC1 (0.47) | MAOBMAOANPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3728339-B1 | COMPOSITION FOR OPHTHALMOLOGICAL PRODUCTS | AMO Ireland (IE) | 2022-07-06 | — | — | EP | disclosed |
| EP-3502147-A1 | COMPOSITION FOR OPHTHALMOLOGICAL PRODUCTS | Merck Patent GmbH (DE) | 2019-06-26 | — | — | EP | disclosed |