Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 10/20 | 0.62 |
| ▸ | GRIN1 | Q05586 | 8/20 | 0.53 |
| ▸ | GRIN2B | Q13224 | 8/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21117369 | 0.91 | PDE4B (0.61) | PDE4BGRIN1GRIN2BHSD17B10 | |
| SCHEMBL21117550 | 0.90 | PDE4B (0.61) | PDE4BGRIN1GRIN2BHSD17B10 | |
| SCHEMBL21087488 | 0.88 | PDE4B (0.64) | PDE4BGRIN1GRIN2BHSD17B10 | |
| SCHEMBL21115761 | 0.87 | GRIN1 (0.54) | PDE4BGRIN1GRIN2BHSD17B10 | |
| SCHEMBL21117398 | 0.86 | PDE4B (0.54) | PDE4BGRIN1GRIN2B | |
| SCHEMBL21117315 | 0.86 | PDE4B (0.60) | PDE4BHSD17B10 | |
| SCHEMBL21117383 | 0.85 | PDE4B (0.61) | PDE4BGRIN1GRIN2BHSD17B10 | |
| SCHEMBL21117316 | 0.85 | PDE4B (0.61) | PDE4BHSD17B10 | |
| SCHEMBL21117745 | 0.85 | PDE4B (0.61) | PDE4BGRIN1GRIN2BHSD17B10 | |
| SCHEMBL21117380 | 0.84 | PDE4B (0.62) | PDE4BGRIN1GRIN2BHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3502111-A1 | PDE4 INHIBITOR | Shijiazhuang Sagacity New Drug Development Co., Ltd. (CN) | 2019-06-26 | — | — | EP | disclosed |