⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20169449 | 0.78 | — | — | |
| SCHEMBL22515500 | 0.75 | CRBN (0.30) | — | |
| SCHEMBL15170880 | 0.74 | — | — | |
| SCHEMBL16348454 | 0.72 | — | — | |
| SCHEMBL20822027 | 0.70 | — | — | |
| SCHEMBL20068402 | 0.69 | — | — | |
| SCHEMBL13065453 | 0.69 | — | — | |
| SCHEMBL7588464 | 0.69 | — | — | |
| SCHEMBL7588453 | 0.69 | — | — | |
| SCHEMBL19197231 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11040945-B2 | Tubulin inhibitors | LIN BIOSCIENCE PTY LTD. | 2021-06-22 | — | — | US | disclosed |
| US-20190169127-A1 | TUBULIN INHIBITORS | LIN BIOSCIENCE INC. (TW) | 2019-06-06 | — | — | US | disclosed |