SCHEMBL2111928

SCHEMBL2111928

COc1ccc(C(=O)N(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.73
HPGD P15428 1/20 0.73
KMT2A Q03164 3/20 0.59
CES2 O00748 2/20 0.59
CES1 P23141 2/20 0.59
TRPM8 Q7Z2W7 1/20 0.56
CA1 P00915 1/20 0.55
CA2 P00918 1/20 0.55
HSD17B1 P14061 1/20 0.54
HSD17B2 P37059 1/20 0.54
NPC1 O15118 2/20 0.53
RAB9A P51151 2/20 0.53
NPSR1 Q6W5P4 1/20 0.53
TSHR P16473 2/20 0.52
MEN1 O00255 2/20 0.51
OPRM1 P35372 1/20 0.51
OPRL1 P41146 1/20 0.51
HTT P42858 1/20 0.50
NR3C2 P08235 1/20 0.49
ACHE P22303 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2113520 0.98 KDM4E (0.71) KDM4EHPGDKMT2ACES2CES1
SCHEMBL2112561 0.95 KDM4E (0.66) KDM4EHPGDKMT2ACES2CES1
SCHEMBL2112872 0.93 KDM4E (0.63) KDM4EHPGDKMT2ACES2CES1
SCHEMBL11874843 0.92 KDM4E (0.63) KDM4EHPGDKMT2ACES2CES1
SCHEMBL2112170 0.91 HSD17B2 (0.64) KDM4EHPGDKMT2ACES2CES1
SCHEMBL2112462 0.91 KDM4E (0.59) KDM4EHPGDKMT2ACES2CES1
SCHEMBL29275131 0.88 HSD17B2 (0.65) KDM4EHPGDKMT2ACES2CES1
SCHEMBL2112987 0.87 KDM4E (0.57) KDM4EHPGDKMT2ACES2CES1
SCHEMBL7865528 0.86 KDM4E (0.69) KDM4EHPGDKMT2ACES2CES1
SCHEMBL6300805 0.86 HSD17B2 (0.59) KDM4EHPGDKMT2ACES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 143 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008130571-A1 NUCLEAR RECEPTOR BINDING AGENTS GTX, INC. (US) 2008-10-30 WO claimed
US-20070265296-A1 Nuclear receptor binding agents GTX, INC. 2007-11-15 US claimed
CN-114729106-B Epoxy resin composition, prepreg and fiber-reinforced composite material 东丽株式会社 2024-03-05 CN disclosed
US-20230288610-A1 WAVELENGTH SELECTIVE ABSORPTION FILTER AND DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2023-09-14 US disclosed
CN-116041198-A Method for synthesizing amide derivative by vanadium catalysis 陕西师范大学 2023-05-02 CN disclosed
CN-114729109-A Epoxy resin composition, prepreg, and fiber-reinforced composite material 东丽株式会社 2022-07-08 CN disclosed
CN-114729108-A Epoxy resin composition, prepreg, and fiber-reinforced composite material 东丽株式会社 2022-07-08 CN disclosed
CN-114729106-A Epoxy resin composition, prepreg, and fiber-reinforced composite material 东丽株式会社 2022-07-08 CN disclosed
WO-2021095631-A1 EPOXY RESIN COMPOSITION, PREPREG, AND FIBER-REINFORCED COMPOSITE MATERIAL 東レ株式会社 2021-05-20 WO disclosed
WO-2021095629-A1 EPOXY RESIN COMPOSITION, PREPREG, AND FIBER-REINFORCED COMPOSITE MATERIAL 東レ株式会社 2021-05-20 WO disclosed
WO-2021095627-A1 EPOXY RESIN COMPOSITION, PREPREG, AND FIBER-REINFORCED COMPOSITE MATERIAL 東レ株式会社 2021-05-20 WO disclosed
US-20070259134-A1 Cellulose Compound Film, Optical Compensation Sheet, Polarizing Plate, and Liquid Crystal Display Device FUJIFILM CORPORATION (JP) 2007-11-08 US disclosed
US-20070195226-A1 Polarizing plate and liquid crystal display FUJIFILM CORPORATION (JP) 2007-08-23 US disclosed
US-20070195226-A1 Polarizing plate and liquid crystal display FUJIFILM CORPORATION (JP) 2007-08-23 US disclosed
WO-2007061139-A1 CELLULOSE ACYLATE FILM, METHOD OF PRODUCING THE SAME, CELLULOSE DERIVATIVE FILM, OPTICALLY COMPENSATORY FILM USING THE SAME, OPTICALLY-COMPENSATORY FILM INCORPORATING POLARIZING PLATE, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2007-05-31 WO disclosed
US-20070076155-A1 Optical film, optical compensation film, polarizing plate and liquid crystal display FUJI PHOTO FILM CO., LTD. (JP) 2007-04-05 US disclosed
US-20070076155-A1 Optical film, optical compensation film, polarizing plate and liquid crystal display FUJI PHOTO FILM CO., LTD. (JP) 2007-04-05 US disclosed
WO-2007029843-A1 POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE USING THE SAME FUJIFILM CORPORATION (JP) 2007-03-15 WO disclosed
US-20070059458-A1 Cellulose acylate film, optically compensatory film, polarizing plate and liquid crystal display FUJI PHOTO FILM CO., LTD. (JP) 2007-03-15 US disclosed
US-20070059458-A1 Cellulose acylate film, optically compensatory film, polarizing plate and liquid crystal display FUJI PHOTO FILM CO., LTD. (JP) 2007-03-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070265296-A1 Nuclear receptor binding agents GPER1, ESRRG, ESR2 KDM4E 1462/4885HPGD 1070/4885KMT2A 1506/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.