⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15561708 | 0.94 | — | — | |
| SCHEMBL21130144 | 0.90 | — | — | |
| SCHEMBL21130134 | 0.89 | — | — | |
| SCHEMBL21130229 | 0.88 | — | — | |
| SCHEMBL21129720 | 0.88 | — | — | |
| SCHEMBL15561879 | 0.87 | — | — | |
| SCHEMBL21129709 | 0.86 | — | — | |
| SCHEMBL15917918 | 0.86 | — | — | |
| SCHEMBL21129972 | 0.86 | POLB (0.52) | — | |
| SCHEMBL21130133 | 0.86 | SCN8A (0.56) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2951155-B1 | AMIDES AS MODULATORS OF SODIUM CHANNELS | VERTEX PHARMA (US) | 2019-06-19 | — | — | EP | disclosed |