Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR4 | P22455 | 10/20 | 0.72 |
| ▸ | FGFR1 | P11362 | 8/20 | 0.72 |
| ▸ | FGFR3 | P22607 | 6/20 | 0.72 |
| ▸ | FGFR2 | P21802 | 8/20 | 0.67 |
| ▸ | TNK2 | Q07912 | 4/20 | 0.41 |
| ▸ | KDR | P35968 | 2/20 | 0.39 |
| ▸ | BTK | Q06187 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21131363 | 1.00 | FGFR4 (0.72) | FGFR4FGFR1FGFR3FGFR2TNK2 | |
| SCHEMBL21131365 | 0.87 | FGFR4 (0.74) | FGFR4FGFR1FGFR3FGFR2TNK2 | |
| SCHEMBL29592326 | 0.84 | FGFR3 (0.86) | FGFR4FGFR1FGFR3FGFR2TNK2 | |
| SCHEMBL21056236 | 0.84 | FGFR4 (1.00) | FGFR4FGFR1FGFR3FGFR2KDR | |
| SCHEMBL21050832 | 0.84 | FGFR4 (1.00) | FGFR4FGFR1FGFR3FGFR2KDR | |
| SCHEMBL21050780 | 0.84 | FGFR4 (1.00) | FGFR4FGFR1FGFR3FGFR2KDR | |
| SCHEMBL21091458 | 0.84 | FGFR4 (1.00) | FGFR4FGFR1FGFR3FGFR2KDR | |
| SCHEMBL21056238 | 0.84 | FGFR4 (1.00) | FGFR4FGFR1FGFR3FGFR2KDR | |
| SCHEMBL21050975 | 0.84 | FGFR4 (1.00) | FGFR4FGFR1FGFR3FGFR2KDR | |
| SCHEMBL21056242 | 0.83 | FGFR4 (1.00) | FGFR4FGFR1FGFR3FGFR2KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3498706-A1 | HETEROCYCLIC COMPOUND AS FGFR INHIBITOR | Guangzhou InnoCare Pharma Tech Co., Ltd. (CN) | 2019-06-19 | — | — | EP | disclosed |