Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 8/20 | 0.81 |
| ▸ | FGFR2 | P21802 | 10/20 | 0.79 |
| ▸ | FGFR3 | P22607 | 6/20 | 0.79 |
| ▸ | FGFR4 | P22455 | 9/20 | 0.75 |
| ▸ | TNK2 | Q07912 | 2/20 | 0.43 |
| ▸ | KDR | P35968 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21056240 | 0.90 | FGFR4 (0.89) | FGFR1FGFR2FGFR3FGFR4TNK2 | |
| SCHEMBL21050909 | 0.89 | FGFR1 (1.00) | FGFR1FGFR2FGFR3FGFR4KDR | |
| SCHEMBL21050968 | 0.89 | FGFR4 (0.89) | FGFR1FGFR2FGFR3FGFR4 | |
| SCHEMBL21050893 | 0.89 | FGFR2 (1.00) | FGFR1FGFR2FGFR3FGFR4KDR | |
| SCHEMBL21050890 | 0.89 | FGFR2 (1.00) | FGFR1FGFR2FGFR3FGFR4KDR | |
| SCHEMBL21050975 | 0.86 | FGFR4 (1.00) | FGFR1FGFR2FGFR3FGFR4KDR | |
| SCHEMBL21091458 | 0.86 | FGFR4 (1.00) | FGFR1FGFR2FGFR3FGFR4KDR | |
| SCHEMBL21056238 | 0.86 | FGFR4 (1.00) | FGFR1FGFR2FGFR3FGFR4KDR | |
| SCHEMBL21050930 | 0.85 | FGFR4 (1.00) | FGFR1FGFR2FGFR3FGFR4 | |
| SCHEMBL21056237 | 0.84 | FGFR3 (0.73) | FGFR1FGFR2FGFR3FGFR4TNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3498706-A1 | HETEROCYCLIC COMPOUND AS FGFR INHIBITOR | Guangzhou InnoCare Pharma Tech Co., Ltd. (CN) | 2019-06-19 | — | — | EP | disclosed |