SCHEMBL21132135

SCHEMBL21132135

c1ccc(-c2cc(-c3ccc(-c4ccc(-c5nc(-c6ccccc6)nc(-c6ccccc6)n5)cc4)c4ccccc34)cc(-c3ccccc3)n2)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 9/20 0.58
KMT2A Q03164 9/20 0.58
HPGD P15428 6/20 0.58
ALDH1A1 P00352 5/20 0.58
MAPT P10636 5/20 0.58
NTSR1 P30989 1/20 0.53
KDM4E B2RXH2 3/20 0.50
LMNA P02545 2/20 0.50
ADORA2A P29274 1/20 0.50
ADORA1 P30542 1/20 0.50
GLA P06280 1/20 0.50
ACACA Q13085 1/20 0.46
MAPK1 P28482 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
ALOX5 P09917 1/20 0.44
ACHE P22303 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
RXFP1 Q9HBX9 1/20 0.43
CYP2C19 P33261 1/20 0.43
ATM Q13315 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17829305 0.95 MEN1 (0.56) MEN1KMT2AHPGDALDH1A1MAPT
SCHEMBL17829314 0.95 MEN1 (0.56) MEN1KMT2AHPGDALDH1A1MAPT
SCHEMBL18118587 0.93 MEN1 (0.67) MEN1KMT2AHPGDALDH1A1MAPT
SCHEMBL21132136 0.93 MEN1 (0.67) MEN1KMT2AHPGDALDH1A1MAPT
SCHEMBL21131530 0.92 MEN1 (0.53) MEN1KMT2AHPGDALDH1A1MAPT
SCHEMBL17598628 0.92 MEN1 (0.53) MEN1KMT2AHPGDALDH1A1MAPT
SCHEMBL17598585 0.92 MEN1 (0.53) MEN1KMT2AHPGDALDH1A1MAPT
SCHEMBL18965335 0.91 MEN1 (0.65) MEN1KMT2AHPGDALDH1A1MAPT
SCHEMBL14079805 0.91 MEN1 (0.63) MEN1KMT2AHPGDALDH1A1MAPT
SCHEMBL14079802 0.91 MEN1 (0.63) MEN1KMT2AHPGDALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11211563-B2 Organic light emitting device LG CHEM, LTD. (KR) 2021-12-28 US disclosed
EP-3498804-B1 ORGANIC LIGHT EMITTING DEVICE LG CHEMICAL LTD (KR) 2020-06-03 EP disclosed
US-20190198766-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2019-06-27 US disclosed