Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | ALPG | P10696 | 1/20 | 0.55 |
| ▸ | PIM1 | P11309 | 2/20 | 0.48 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.48 |
| ▸ | CDK2 | P24941 | 2/20 | 0.46 |
| ▸ | AURKA | O14965 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.46 |
| ▸ | IKBKB | O14920 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.46 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.46 |
| ▸ | PRKCG | P05129 | 1/20 | 0.46 |
| ▸ | CDK1 | P06493 | 1/20 | 0.46 |
| ▸ | LYN | P07948 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL721045 | 0.76 | APP (0.55) | MAPTMEN1KMT2ARAB9ATDP1 | |
| SCHEMBL26779179 | 0.75 | GAA (0.46) | MAPTMEN1KMT2AKDM4EPIM1 | |
| SCHEMBL248683 | 0.74 | ELANE (0.50) | MEN1KMT2AKDM4EELANEHSD17B10 | |
| SCHEMBL10583833 | 0.74 | HSD17B10 (0.47) | MAPTMEN1KMT2ARAB9ATDP1 | |
| SCHEMBL5057841 | 0.73 | SCN9A (0.41) | MAPTMEN1KMT2ARAB9ATDP1 | |
| SCHEMBL3759875 | 0.72 | MAPT (1.00) | MAPTMEN1KMT2ARAB9ATDP1 | |
| SCHEMBL15194997 | 0.72 | TAAR1 (0.46) | MAPTMEN1KMT2ARAB9ATDP1 | |
| SCHEMBL210467 | 0.72 | KMT2A (0.64) | MAPTMEN1KMT2ARAB9ACDK2 | |
| SCHEMBL5822932 | 0.72 | MAPK1 (0.35) | MAPTMEN1KMT2ARAB9ATDP1 | |
| SCHEMBL8944768 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7851456-B2 | P2Y6 receptor agonists for treating lung diseases | INSPIRE PHARMACEUTICALS, INC. (US) | 2010-12-14 | — | — | US | claimed |
| EP-1895840-A2 | P2Y6 RECEPTOR AGONISTS FOR TREATING LUNG DISEASES | Inspire Pharmaceuticals, Inc. (US) | 2008-03-12 | — | — | EP | claimed |
| US-20070015726-A1 | P2Y6 receptor agonists for treating lung diseases | MERCK SHARP & DOHME LLC | 2007-01-18 | — | — | US | claimed |
| WO-2007002945-A2 | P2Y6 RECEPTOR AGONISTS FOR TREATING LUNG DISEASES | INSPIRE PHARMACEUTICALS, INC. (US) | 2007-01-04 | — | — | WO | claimed |
| EP-0981958-B1 | INSECTICIDAL/ACARICIDAL AGENTS | SAGAMI CHEM RES (JP) | 2004-03-31 | — | — | EP | claimed |
| US-6548511-B1 | Anilinopyrimidinone derivatives of given formula such as 2-(2,5-bis(trifluoromethyl)phenyl)amino-5-chloro-3-isobutyl-6 -trifluoromethyl-4(3H)-pyrimidinone; controlling pests of agricultural and horticultural products | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 2003-04-15 | — | — | US | claimed |
| EP-0981958-A1 | INSECTICIDAL/ACARICIDAL AGENTS | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 2000-03-01 | — | — | EP | claimed |
| US-8158776-B2 | P2Y6 receptor agonists for treating lung diseases | INSPIRE PHARMACEUTICALS, INC. (US) | 2012-04-17 | — | — | US | disclosed |
| US-20110054163-A1 | P2Y6 RECEPTOR AGONISTS FOR TREATING LUNG DISEASES | MERCK SHARP & DOHME LLC | 2011-03-03 | — | — | US | disclosed |
| US-7851456-B2 | P2Y6 receptor agonists for treating lung diseases | INSPIRE PHARMACEUTICALS, INC. (US) | 2010-12-14 | — | — | US | disclosed |
| EP-1895840-A2 | P2Y6 RECEPTOR AGONISTS FOR TREATING LUNG DISEASES | Inspire Pharmaceuticals, Inc. (US) | 2008-03-12 | — | — | EP | disclosed |
| US-20070015726-A1 | P2Y6 receptor agonists for treating lung diseases | MERCK SHARP & DOHME LLC | 2007-01-18 | — | — | US | disclosed |
| WO-2007002945-A2 | P2Y6 RECEPTOR AGONISTS FOR TREATING LUNG DISEASES | INSPIRE PHARMACEUTICALS, INC. (US) | 2007-01-04 | — | — | WO | disclosed |
| US-6548511-B1 | Anilinopyrimidinone derivatives of given formula such as 2-(2,5-bis(trifluoromethyl)phenyl)amino-5-chloro-3-isobutyl-6 -trifluoromethyl-4(3H)-pyrimidinone; controlling pests of agricultural and horticultural products | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 2003-04-15 | — | — | US | disclosed |
| US-6548511-B1 | Anilinopyrimidinone derivatives of given formula such as 2-(2,5-bis(trifluoromethyl)phenyl)amino-5-chloro-3-isobutyl-6 -trifluoromethyl-4(3H)-pyrimidinone; controlling pests of agricultural and horticultural products | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 2003-04-15 | — | — | US | disclosed |
| EP-0981958-A4 | INSECTICIDAL/ACARICIDAL AGENTS | SAGAMI CHEM RES (JP) | 2002-07-03 | — | — | EP | disclosed |
| EP-0981958-A1 | INSECTICIDAL/ACARICIDAL AGENTS | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 2000-03-01 | — | — | EP | disclosed |
| EP-0981958-A1 | INSECTICIDAL/ACARICIDAL AGENTS | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 2000-03-01 | — | — | EP | disclosed |
| WO-1998051152-A1 | INSECTICIDAL/ACARICIDAL AGENTS | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1998-11-19 | — | — | WO | disclosed |
| WO-1998051675-A1 | ANILINOPYRIMIDINONE DERIVATIVES, PROCESSES FOR PRODUCING THE SAME, AND INSECTICIDAL/ACARICIDAL AGENTS CONTAINING THE SAME AS ACTIVE INGREDIENT | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1998-11-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110054163-A1 | P2Y6 RECEPTOR AGONISTS FOR TREATING LUNG DISEASES | P2RY6, P2RY1, P2RY11 | MAPT 4587/4885MEN1 2871/4885KMT2A 4361/4885 |
| US-20070015726-A1 | P2Y6 receptor agonists for treating lung diseases | P2RY6, P2RY1, P2RY11 | MAPT 4558/4885MEN1 2911/4885KMT2A 4415/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.