Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNRHR | P30968 | 20/20 | 0.86 |
| ▸ | CYP3A4 | P08684 | 12/20 | 0.83 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.76 |
| ▸ | APLNR | P35414 | 1/20 | 0.76 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.76 |
| ▸ | GLP1R | P43220 | 1/20 | 0.76 |
| ▸ | CX3CR1 | P49238 | 1/20 | 0.76 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.76 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23193840 | 1.00 | GNRHR (0.86) | GNRHRCYP3A4ADRB2APLNROPRK1 | |
| SCHEMBL21694890 | 0.93 | GNRHR (0.82) | GNRHRCYP3A4ADRB2APLNROPRK1 | |
| SCHEMBL30153581 | 0.93 | GNRHR (0.84) | GNRHRCYP3A4ADRB2APLNROPRK1 | |
| SCHEMBL1653132 | 0.92 | GNRHR (0.84) | GNRHRCYP3A4ADRB2APLNROPRK1 | |
| SCHEMBL20547884 | 0.92 | GNRHR (0.86) | GNRHRCYP3A4ADRB2APLNROPRK1 | |
| SCHEMBL20547883 | 0.92 | GNRHR (0.86) | GNRHRCYP3A4ADRB2APLNROPRK1 | |
| SCHEMBL21694889 | 0.92 | GNRHR (0.80) | GNRHRCYP3A4ADRB2APLNROPRK1 | |
| SCHEMBL21694888 | 0.91 | GNRHR (0.84) | GNRHRCYP3A4ADRB2APLNROPRK1 | |
| SCHEMBL2701302 | 0.90 | GNRHR (0.82) | GNRHRCYP3A4ADRB2APLNROPRK1 | |
| SCHEMBL22487833 | 0.90 | GNRHR (0.83) | GNRHRCYP3A4ADRB2APLNROPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019115019-A1 | PROCESS FOR PREPARING ELAGOLIX | SYNTHON B.V. (NL) | 2019-06-20 | — | — | WO | disclosed |