SCHEMBL2113409

SCHEMBL2113409

NCCCCC(N)C(=O)N1CCC[C@@H]1C(=O)O

nearest known ligand 0.65

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
DPP7 Q9UHL4 6/20 0.65
DPP4 P27487 4/20 0.65
DPP8 Q6V1X1 4/20 0.65
DPP9 Q86TI2 2/20 0.65
FAP Q12884 1/20 0.65
ACE P12821 2/20 0.54
REN P00797 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2123080 1.00 DPP7 (0.65) DPP7DPP4DPP8DPP9FAP
SCHEMBL27796855 1.00 DPP7 (0.65) DPP7DPP4DPP8DPP9FAP
SCHEMBL2113410 1.00 DPP7 (0.65) DPP7DPP4DPP8DPP9FAP
SCHEMBL2123083 1.00 DPP7 (0.65) DPP7DPP4DPP8DPP9FAP
SCHEMBL29374265 1.00 DPP7 (0.65) DPP7DPP4DPP8DPP9FAP
SCHEMBL2113944 0.96 DPP4 (0.59) DPP7DPP4DPP8DPP9FAP
SCHEMBL29610030 0.96 DPP4 (0.59) DPP7DPP4DPP8DPP9FAP
SCHEMBL2113947 0.96 DPP4 (0.59) DPP7DPP4DPP8DPP9FAP
SCHEMBL11017609 0.95 DPP7 (0.60) DPP7DPP4DPP8DPP9FAP
SCHEMBL10829152 0.95 DPP7 (0.60) DPP7DPP4DPP8DPP9FAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1323730-B1 NOVEL POLYPEPTIDES AND ANTI-HIV DRUGS CONTAINING THE SAME BIOKINE THERAPEUTICS LTD (IL) 2010-04-21 EP claimed
US-20100055088-A1 CXCR4 Antagonists for Wound Healing and Re-Epithelialization HADASIT MEDICAL RESEARCH SERVICES AND DEVELOPMENT LTD. (IL) 2010-03-04 US claimed
EP-1898943-A2 CXCR4 ANTAGONISTS FOR WOUND HEALING AND RE-EPITHELIALIZATION Hadasit Medical Research Services & Development Ltd. (IL) 2008-03-19 EP claimed
WO-2006126188-A2 CXCR4 ANTAGONISTS FOR WOUND HEALING AND RE-EPITHELIALIZATION HADASIT MEDICAL RESEARCH SERVICES AND DEVELOPMENT LTD. (IL) 2006-11-30 WO claimed
US-20040116655-A1 Novel polypeptides and anti-hiv drugs containing the same BIOKINE THERAPEUTICS LTD. (IL) 2004-06-17 US claimed
EP-1323730-A1 NOVEL POLYPEPTIDES AND ANTI-HIV DRUGS CONTAINING THE SAME SEIKAGAKU CORPORATION (JP) 2003-07-02 EP claimed
EP-0677061-B1 POLYPEPTIDES AND ANTI-HIV AGENTS PREPARED THEREFROM SEIKAGAKU KOGYO CO LTD (JP) 1999-03-03 EP claimed
US-5776899-A Polypeptide and anti-HIV agent prepared therefrom SEIKAGAKU CORPORATION (JP) 1998-07-07 US claimed
EP-0677061-A1 POLYPEPTIDE AND ANTI-HIV AGENT PREPARED THEREFROM SEIKAGAKU CORPORATION (JP) 1995-10-18 EP claimed
WO-1995010534-A1 POLYPEPTIDE AND ANTI-HIV AGENT PREPARED THEREFROM SEIKAGAKU CORPORATION (JP) 1995-04-20 WO claimed
EP-3011961-B1 4F-BENZOYL-TN14003 FOR THE MOBILISATION OF HEMATOPOIETIC PROGENITOR CELLS IN VIEW OF TRANSPLANTATION BIOKINE THERAPEUTICS LTD (IL) 2020-11-11 EP disclosed
EP-2841084-B1 CXCR4 ANTAGONIST PEPTIDE FOR USE IN THE TREATMENT OF LARGE CELL LUNG CANCER BIOKINE THERAPEUTICS LTD (IL) 2018-05-30 EP disclosed
US-9439942-B2 Peptides and use thereof in the treatment of large cell lung cancer BIOKINE THERAPEUTICS LTD. (IL) 2016-09-13 US disclosed
US-9427456-B2 Peptide therapy for increasing platelet levels BIOKINE THERAPEUTICS LTD. (IL) 2016-08-30 US disclosed
EP-3011961-A1 4F-benzoyl-TN14003 for the mobilisation of hematopoietic progenitor cells in view of transplantation Biokine Therapeutics LTD. (IL) 2016-04-27 EP disclosed
CN-1116427-A Novel polypeptide and anti-HIV agent prepared from the same SEIKAGAKU KOGYO CO LTD (JP) 1996-02-07 CN disclosed
EP-0677061-A1 POLYPEPTIDE AND ANTI-HIV AGENT PREPARED THEREFROM SEIKAGAKU CORPORATION (JP) 1995-10-18 EP disclosed
EP-0677061-A1 POLYPEPTIDE AND ANTI-HIV AGENT PREPARED THEREFROM SEIKAGAKU CORPORATION (JP) 1995-10-18 EP disclosed
WO-1995010534-A1 POLYPEPTIDE AND ANTI-HIV AGENT PREPARED THEREFROM SEIKAGAKU CORPORATION (JP) 1995-04-20 WO disclosed
WO-1995010534-A1 POLYPEPTIDE AND ANTI-HIV AGENT PREPARED THEREFROM SEIKAGAKU CORPORATION (JP) 1995-04-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100055088-A1 CXCR4 Antagonists for Wound Healing and Re-Epithelialization CXCR4, CXCL12, CXCR5 DPP7 1920/4885DPP4 1637/4885DPP8 2093/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.