Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.30 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15998885 | 0.80 | EPHX1 (0.40) | EPHX1 | |
| SCHEMBL11170476 | 0.78 | CHRM1 (0.35) | CHRM1CHRM2CHRM4CHRM5CHRM3 | |
| SCHEMBL9941967 | 0.72 | — | — | |
| SCHEMBL27284139 | 0.72 | — | — | |
| SCHEMBL18925003 | 0.69 | — | — | |
| SCHEMBL3462902 | 0.68 | EPHX1 (0.44) | EPHX1CHRM1CHRM2CHRM4CHRM5 | |
| SCHEMBL17586264 | 0.68 | CHRM1 (0.34) | CHRM1CHRM2CHRM4CHRM5CHRM3 | |
| SCHEMBL1247102 | 0.68 | EPHX1 (0.39) | EPHX1 | |
| SCHEMBL1247100 | 0.68 | EPHX1 (0.39) | EPHX1 | |
| SCHEMBL30984016 | 0.67 | CHRM1 (0.41) | CHRM1CHRM2CHRM4CHRM5CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE47493-E1 | Substituted bicyclic dihydropyrimidinones and their use as inhibitors of neutrophil elastase activity | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2019-07-09 | — | — | US | disclosed |