Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIKFYVE | Q9Y2I7 | 11/20 | 0.69 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.51 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.51 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.51 |
| ▸ | MTOR | P42345 | 2/20 | 0.51 |
| ▸ | FES | P07332 | 1/20 | 0.49 |
| ▸ | FER | P16591 | 1/20 | 0.49 |
| ▸ | TYK2 | P29597 | 1/20 | 0.49 |
| ▸ | FRK | P42685 | 1/20 | 0.49 |
| ▸ | SYK | P43405 | 1/20 | 0.49 |
| ▸ | CAMK1D | Q8IU85 | 1/20 | 0.49 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22727780 | 0.83 | PIKFYVE (0.64) | PIKFYVELMNAMAPTKDM4EHPGD | |
| SCHEMBL22727824 | 0.83 | PIKFYVE (0.67) | PIKFYVELMNAMAPTKDM4EHPGD | |
| SCHEMBL22727807 | 0.83 | PIKFYVE (0.64) | PIKFYVELMNAMAPTKDM4EHPGD | |
| SCHEMBL13548872 | 0.82 | GAA (0.70) | PIKFYVELMNAMAPTKDM4EHPGD | |
| SCHEMBL24100159 | 0.82 | PIKFYVE (0.68) | PIKFYVELMNAMAPTKDM4EHPGD | |
| SCHEMBL22718389 | 0.82 | PIKFYVE (0.63) | PIKFYVELMNAMAPTKDM4EHPGD | |
| SCHEMBL21135813 | 0.82 | PIKFYVE (0.80) | PIKFYVELMNAMAPTKDM4EHPGD | |
| SCHEMBL21054187 | 0.82 | PIKFYVE (1.00) | PIKFYVELMNAMAPTKDM4EHPGD | |
| SCHEMBL21054563 | 0.82 | PIKFYVE (1.00) | PIKFYVELMNAMAPTKDM4EHPGD | |
| SCHEMBL30308928 | 0.82 | PIKFYVE (0.68) | PIKFYVELMNAMAPTKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020243457-A1 | COMPOUNDS AND THERAPEUTIC USES THEREOF | VIOGEN BIOSCIENCES, LLC (US) | 2020-12-03 | — | — | WO | disclosed |
| WO-2019113523-A1 | COMPOUNDS AND THERAPEUTIC USES THEREOF | BAJJI ASHOK (US) | 2019-06-13 | — | — | WO | disclosed |