Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIKFYVE | Q9Y2I7 | 10/20 | 0.80 |
| ▸ | PIK3CA | P42336 | 5/20 | 0.51 |
| ▸ | PIK3R1 | P27986 | 3/20 | 0.51 |
| ▸ | MTOR | P42345 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.44 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30312456 | 1.00 | PIKFYVE (0.80) | PIKFYVEPIK3CAPIK3R1MTORLMNA | |
| SCHEMBL21135482 | 0.93 | PIKFYVE (0.81) | PIKFYVEPIK3CAPIK3R1MTORLMNA | |
| SCHEMBL30312440 | 0.93 | PIKFYVE (0.81) | PIKFYVEPIK3CAPIK3R1MTORLMNA | |
| SCHEMBL23272104 | 0.93 | PIKFYVE (0.76) | PIKFYVEPIK3CAPIK3R1MTORLMNA | |
| SCHEMBL30312501 | 0.93 | PIKFYVE (0.76) | PIKFYVEPIK3CAPIK3R1MTORLMNA | |
| SCHEMBL21135484 | 0.92 | PIKFYVE (0.75) | PIKFYVEPIK3CAPIK3R1MTORLMNA | |
| SCHEMBL30312465 | 0.92 | PIKFYVE (0.75) | PIKFYVEPIK3CAPIK3R1MTORLMNA | |
| SCHEMBL30312357 | 0.90 | PIKFYVE (0.73) | PIKFYVEPIK3CAPIK3R1MTORLMNA | |
| SCHEMBL23272145 | 0.90 | PIKFYVE (0.73) | PIKFYVEPIK3CAPIK3R1MTORLMNA | |
| SCHEMBL21054818 | 0.90 | PIKFYVE (0.87) | PIKFYVEPIK3CAPIK3R1MTORLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11603372-B2 | Compounds and therapeutic uses thereof | VIOGEN BIOSCIENCES, LLC (US) | 2023-03-14 | — | — | US | claimed |
| US-20210122752-A1 | COMPOUNDS AND THERAPEUTIC USES THEREOF | VIOGEN BIOSCIENCES, LLC | 2021-04-29 | — | — | US | claimed |
| US-20240016810-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT AND PREVENTION OF NEUROLOGICAL DISORDERS | YUMANITY THERAPEUTICS, INC. | 2024-01-18 | — | — | US | disclosed |
| US-20240016810-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT AND PREVENTION OF NEUROLOGICAL DISORDERS | YUMANITY THERAPEUTICS, INC. | 2024-01-18 | — | — | US | disclosed |
| US-11603372-B2 | Compounds and therapeutic uses thereof | VIOGEN BIOSCIENCES, LLC (US) | 2023-03-14 | — | — | US | disclosed |
| US-20210122752-A1 | COMPOUNDS AND THERAPEUTIC USES THEREOF | VIOGEN BIOSCIENCES, LLC | 2021-04-29 | — | — | US | disclosed |
| US-20210122752-A1 | COMPOUNDS AND THERAPEUTIC USES THEREOF | VIOGEN BIOSCIENCES, LLC | 2021-04-29 | — | — | US | disclosed |
| WO-2019113523-A1 | COMPOUNDS AND THERAPEUTIC USES THEREOF | BAJJI ASHOK (US) | 2019-06-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240016810-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT AND PREVENTION OF NEUROLOGICAL DISORDERS | TARDBP, PIKFYVE, FUS | PIKFYVE 2/4885PIK3CA 252/4885PIK3R1 207/4885 |
| US-11603372-B2 | Compounds and therapeutic uses thereof | IL15, IL17A, IL2 | PIKFYVE 944/4885PIK3CA 1586/4885PIK3R1 2776/4885 |
| US-20210122752-A1 | COMPOUNDS AND THERAPEUTIC USES THEREOF | IL15, IL17A, IL2 | PIKFYVE 944/4885PIK3CA 1586/4885PIK3R1 2776/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.