Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP26A1 | O43174 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.35 |
| ▸ | TBXA2R | P21731 | 5/20 | 0.32 |
| ▸ | STS | P08842 | 1/20 | 0.31 |
| ▸ | CTSL | P07711 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21138385 | 0.84 | NAMPT (0.36) | CYP26A1HPGDNAMPTCYP24A1STS | |
| SCHEMBL21138912 | 0.76 | HPGD (0.42) | HPGDNAMPTSTSCTSL | |
| SCHEMBL19916995 | 0.71 | HPGD (0.42) | HPGDNAMPTSTS | |
| SCHEMBL21138390 | 0.68 | HPGD (0.41) | HPGDNAMPTSTS | |
| SCHEMBL21057412 | 0.67 | — | — | |
| SCHEMBL21057413 | 0.67 | — | — | |
| SCHEMBL3620841 | 0.66 | HPGD (0.42) | HPGDNAMPT | |
| SCHEMBL13424419 | 0.65 | BCHE (0.38) | — | |
| SCHEMBL21057476 | 0.64 | HPGD (0.40) | HPGDNAMPTCTSL | |
| SCHEMBL21057473 | 0.64 | HPGD (0.40) | HPGDNAMPTCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190185479-A1 | BICYCLIC NITROGENATED HETEROCYCLIC COMPOUND | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2019-06-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190185479-A1 | BICYCLIC NITROGENATED HETEROCYCLIC COMPOUND | PDE7B, PDE3A, PDE7A | CYP26A1 1653/4885HPGD 252/4885NAMPT 289/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.