Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16217547 | 1.00 | PRMT5 (0.76) | PRMT5WDR77 | |
| SCHEMBL16217546 | 0.91 | PRMT5 (0.81) | PRMT5WDR77 | |
| SCHEMBL21139764 | 0.91 | PRMT5 (0.81) | PRMT5WDR77 | |
| SCHEMBL21139776 | 0.89 | PRMT5 (0.78) | PRMT5WDR77 | |
| SCHEMBL16220708 | 0.89 | PRMT5 (0.78) | PRMT5WDR77 | |
| SCHEMBL16217453 | 0.89 | PRMT5 (0.65) | PRMT5WDR77 | |
| SCHEMBL21140473 | 0.87 | PRMT5 (0.78) | PRMT5WDR77 | |
| SCHEMBL16217538 | 0.87 | PRMT5 (0.78) | PRMT5WDR77 | |
| SCHEMBL21137848 | 0.87 | PRMT5 (0.80) | PRMT5WDR77 | |
| SCHEMBL16217502 | 0.87 | PRMT5 (0.80) | PRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4219465-A2 | PRMT5 INHIBITORS AND USES THEREOF | Epizyme Inc (US) | 2023-08-02 | — | — | EP | disclosed |
| EP-3498701-B1 | PRMT5 INHIBITORS AND USES THEREOF | EPIZYME INC (US) | 2023-02-22 | — | — | EP | disclosed |
| EP-3498701-A1 | PRMT5 INHIBITORS AND USES THEREOF | Epizyme Inc (US) | 2019-06-19 | — | — | EP | disclosed |