SCHEMBL21141000

SCHEMBL21141000

c1ccc2c(c1)-c1ccccc1-c1ccc(N(c3ccc4c(c3)oc3ccccc34)c3cccc4c3-c3ccccc3C43c4ccccc4-c4ccccc43)cc1-c1ccccc1-2

nearest known ligand 0.34

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
AHR P35869 2/20 0.34
MEN1 O00255 2/20 0.33
MAPT P10636 2/20 0.33
KMT2A Q03164 2/20 0.33
KDM4E B2RXH2 1/20 0.33
ALDH1A1 P00352 1/20 0.33
HPGD P15428 1/20 0.33
ALOX5 P09917 1/20 0.32
HTR2B P41595 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24088456 0.96 AHR (0.36) AHRMEN1MAPTKMT2AKDM4E
SCHEMBL25145494 0.95 AHR (0.34) AHRMEN1MAPTKMT2AKDM4E
SCHEMBL25472849 0.94 AHR (0.36) AHRMEN1MAPTKMT2AKDM4E
SCHEMBL18457470 0.93 AHR (0.34) AHRMEN1MAPTKMT2AKDM4E
SCHEMBL19218590 0.93 AHR (0.34) AHRMEN1MAPTKMT2AKDM4E
SCHEMBL21141158 0.93 AHR (0.34) AHRMEN1MAPTKMT2AKDM4E
SCHEMBL21141188 0.92 AHR (0.32) AHRMEN1MAPTKMT2AKDM4E
SCHEMBL18457973 0.92 AHR (0.35) AHRMEN1MAPTKMT2AKDM4E
SCHEMBL24647693 0.91 KDM4E (0.33) AHRMEN1MAPTKMT2AKDM4E
SCHEMBL24078285 0.91 ALK (0.34) AHRMEN1MAPTKMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11512038-B2 Tetraphenylene triarylamine compounds Beijing Summer Sprout Technology Co., Ltd. (CN) 2022-11-29 US disclosed
US-20190185412-A1 TETRAPHENYLENE TRIARYLAMINE COMPOUNDS Beijing Summer Sprout Technology Co., Ltd. (CN) 2019-06-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11512038-B2 Tetraphenylene triarylamine compounds OCIAD2, OCIAD1, SLC7A5 AHR 277/4885MEN1 3882/4885MAPT 1336/4885
US-20190185412-A1 TETRAPHENYLENE TRIARYLAMINE COMPOUNDS OCIAD2, OCIAD1, SLC7A5 AHR 277/4885MEN1 3882/4885MAPT 1336/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.