SCHEMBL21149199

SCHEMBL21149199

c1ccc(-c2cccc(-c3nc(-c4ccc5c6ccccc6c6ccccc6c5c4)nc(-c4cccc5sc6ccccc6c45)n3)c2)cc1

nearest known ligand 0.37

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
F9 P00740 1/20 0.36
PIM3 Q86V86 1/20 0.36
LIMK1 P53667 3/20 0.34
ALOX5 P09917 1/20 0.33
PIK3CA P42336 1/20 0.33
PI4KA P42356 1/20 0.33
PI4KB Q9UBF8 1/20 0.33
MAP3K8 P41279 3/20 0.33
ROCK1 Q13464 1/20 0.33
BRDT Q58F21 1/20 0.32
GP6 Q9HCN6 1/20 0.32
GPR3 P46089 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25557519 0.97 F9 (0.36) F9PIM3LIMK1ALOX5BRDT
SCHEMBL21149206 0.96 F9 (0.36) F9PIM3LIMK1ALOX5BRDT
SCHEMBL25730587 0.95 PIM3 (0.37) F9PIM3LIMK1ALOX5PIK3CA
SCHEMBL21149202 0.95 F9 (0.37) F9PIM3LIMK1ALOX5BRDT
SCHEMBL23138635 0.94 F9 (0.35) F9PIM3LIMK1ALOX5ROCK1
SCHEMBL21149104 0.94 LIMK1 (0.36) F9PIM3LIMK1ALOX5PIK3CA
SCHEMBL21149210 0.94 F9 (0.38) F9PIM3LIMK1ALOX5PIK3CA
SCHEMBL21148189 0.94 ADORA2A (0.36) F9PIM3ALOX5PIK3CAPI4KA
SCHEMBL21149195 0.94 ADORA2A (0.36) F9PIM3ALOX5PIK3CAPI4KA
SCHEMBL21148192 0.94 F9 (0.37) F9PIM3LIMK1ALOX5PIK3CA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230329097-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE SAMSUNG SDI CO LTD (KR) 2023-10-12 US disclosed
US-20230329097-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE SAMSUNG SDI CO LTD (KR) 2023-10-12 US disclosed
US-20190214573-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2019-07-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190214573-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE OR10J3, OCIAD2, OCIAD1 F9 479/4885PIM3 3857/4885LIMK1 133/4885
US-20230329097-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE OR10J3, OCIAD2, OCIAD1 F9 479/4885PIM3 3857/4885LIMK1 133/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.