Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 16/20 | 0.73 |
| ▸ | CA1 | P00915 | 15/20 | 0.73 |
| ▸ | CA2 | P00918 | 15/20 | 0.73 |
| ▸ | CA12 | O43570 | 7/20 | 0.73 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.69 |
| ▸ | CA7 | P43166 | 2/20 | 0.69 |
| ▸ | HTR3A | P46098 | 2/20 | 0.60 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21728989 | 1.00 | CA9 (0.73) | CA9CA1CA2CA12CA14 | |
| SCHEMBL21282083 | 0.93 | CA1 (0.70) | CA9CA1CA2CA12CA14 | |
| SCHEMBL17245251 | 0.93 | CA1 (0.70) | CA9CA1CA2CA12CA14 | |
| SCHEMBL22855043 | 0.93 | CA1 (0.70) | CA9CA1CA2CA12CA14 | |
| SCHEMBL21183301 | 0.93 | CA1 (0.70) | CA9CA1CA2CA12CA14 | |
| SCHEMBL18163373 | 0.92 | CA9 (0.68) | CA9CA1CA2CA12CA14 | |
| SCHEMBL20622624 | 0.92 | CA9 (0.75) | CA9CA1CA2CA12CA14 | |
| SCHEMBL12608907 | 0.91 | CA9 (0.76) | CA9CA1CA2CA12CA14 | |
| SCHEMBL21728982 | 0.90 | CA1 (0.66) | CA9CA1CA2CA12CA14 | |
| SCHEMBL21151022 | 0.90 | CA1 (0.66) | CA9CA1CA2CA12CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019136442-A1 | CD16A BINDING AGENTS AND USES THEREOF | KLEO PHARMACEUTICALS, INC. (US) | 2019-07-11 | — | — | WO | disclosed |