Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.49 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.47 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.47 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.47 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 3/20 | 0.46 |
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | CA2 | P00918 | 3/20 | 0.46 |
| ▸ | CA9 | Q16790 | 3/20 | 0.46 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.46 |
| ▸ | CNR1 | P21554 | 3/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | IDE | P14735 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21026765 | 0.84 | TDP1 (0.59) | TDP1F2PRSS1PRSS2PRSS3 | |
| SCHEMBL19891980 | 0.84 | TDP1 (0.59) | TDP1F2PRSS1PRSS2PRSS3 | |
| SCHEMBL12742901 | 0.80 | TDP1 (0.64) | TDP1F2PRSS1PRSS2PRSS3 | |
| SCHEMBL17929732 | 0.76 | TDP1 (0.59) | TDP1F2PRSS1PRSS2PRSS3 | |
| SCHEMBL17923838 | 0.76 | TDP1 (0.59) | TDP1F2PRSS1PRSS2PRSS3 | |
| SCHEMBL9412852 | 0.76 | TDP1 (0.74) | TDP1F2PRSS1PRSS2PRSS3 | |
| SCHEMBL27414507 | 0.75 | TDP1 (0.63) | TDP1F2PRSS1PRSS2PRSS3 | |
| SCHEMBL27414509 | 0.75 | TDP1 (0.66) | TDP1F2PRSS1PRSS2PRSS3 | |
| SCHEMBL17170007 | 0.75 | TDP1 (0.66) | TDP1F2PRSS1PRSS2PRSS3 | |
| SCHEMBL20006788 | 0.75 | TDP1 (0.67) | TDP1F2PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3245514-B1 | MACROMOLECULAR CONJUGATES FOR VISUALIZATION AND SEPARATION OF PROTEINS AND CELLS | USTAV ORGANICKE CHEMIE A BIOCHEMIE AV CR V V I (CZ) | 2019-07-10 | — | — | EP | disclosed |