Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | RET | P07949 | 6/20 | 0.33 |
| ▸ | DRD1 | P21728 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ATR | Q13535 | 1/20 | 0.32 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.32 |
| ▸ | RXRA | P19793 | 1/20 | 0.31 |
| ▸ | RXRB | P28702 | 1/20 | 0.31 |
| ▸ | RXRG | P48443 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17675453 | 0.83 | GAA (0.49) | GAACYP4F2CYP4A11LMNAALDH1A1 | |
| SCHEMBL21002088 | 0.83 | GAA (0.49) | GAACYP4F2CYP4A11LMNAALDH1A1 | |
| SCHEMBL15445676 | 0.81 | GAA (0.47) | GAACYP4F2CYP4A11LMNAALDH1A1 | |
| SCHEMBL25389805 | 0.80 | GAA (0.46) | GAACYP4F2CYP4A11LMNAALDH1A1 | |
| SCHEMBL15334772 | 0.80 | GAA (0.40) | GAACYP4F2CYP4A11LMNAALDH1A1 | |
| SCHEMBL29250238 | 0.79 | GAA (0.48) | GAACYP4F2CYP4A11LMNAALDH1A1 | |
| SCHEMBL17675672 | 0.79 | GAA (0.45) | GAACYP4F2CYP4A11LMNAALDH1A1 | |
| SCHEMBL15451470 | 0.77 | GAA (0.38) | GAACYP4F2CYP4A11LMNAALDH1A1 | |
| SCHEMBL3082406 | 0.75 | GAA (0.42) | GAACYP4F2CYP4A11 | |
| SCHEMBL22552469 | 0.74 | GAA (0.54) | GAACYP4F2CYP4A11LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3204378-B3 | N-PYRIDINYL ACETAMIDE DERIVATIVES AS INHIBITORS OF THE WNT SIGNALLING PATHWAY | REDX PHARMA PLC (GB) | 2022-05-25 | — | — | EP | disclosed |
| EP-3204378-B1 | N-PYRIDINYL ACETAMIDE DERIVATIVES AS INHIBITORS OF THE WNT SIGNALLING PATHWAY | REDX PHARMA PLC (GB) | 2019-07-10 | — | — | EP | disclosed |