Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21152172 | 0.72 | — | — | |
| SCHEMBL23774977 | 0.72 | — | — | |
| SCHEMBL24415107 | 0.71 | — | — | |
| SCHEMBL21152899 | 0.68 | MEN1 (0.31) | MEN1ALDH1A1MAPTBLMKMT2A | |
| SCHEMBL24174828 | 0.68 | MEN1 (0.31) | MEN1ALDH1A1MAPTBLMKMT2A | |
| SCHEMBL23137828 | 0.68 | MEN1 (0.31) | MEN1ALDH1A1MAPTBLMKMT2A | |
| SCHEMBL23961080 | 0.67 | MEN1 (0.41) | MEN1ALDH1A1MAPTBLMKMT2A | |
| SCHEMBL14752127 | 0.65 | — | — | |
| SCHEMBL24174162 | 0.64 | HTT (0.33) | MEN1ALDH1A1KMT2A | |
| SCHEMBL24174316 | 0.64 | MEN1 (0.31) | MEN1ALDH1A1MAPTBLMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019136025-A1 | ASK1 INHIBITOR COMPOUNDS AND USES THEREOF | Seal Rock Therapeutics, Inc. (US) | 2019-07-11 | — | — | WO | disclosed |