⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9945809 | 0.80 | — | — | |
| SCHEMBL11989936 | 0.80 | — | — | |
| SCHEMBL2616358 | 0.80 | — | — | |
| SCHEMBL18729649 | 0.78 | CETP (0.43) | — | |
| SCHEMBL18729665 | 0.78 | CETP (0.43) | — | |
| SCHEMBL899353 | 0.77 | — | — | |
| SCHEMBL10286008 | 0.77 | — | — | |
| SCHEMBL18759627 | 0.77 | TSHR (0.43) | — | |
| SCHEMBL1682640 | 0.77 | — | — | |
| SCHEMBL27315194 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020146541-A2 | TRACELESS LINKERS AND PROTEIN-CONJUGATES THEREOF | REGENERON PHARMACEUTICALS, INC. (US) | 2020-07-16 | — | — | WO | disclosed |
| US-20190209702-A1 | STEROIDS AND ANTIBODY-CONJUGATES THEREOF | REGENERON PHARMACEUTICALS, INC. | 2019-07-11 | — | — | US | disclosed |