Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGLEC7 | Q9Y286 | 6/20 | 0.52 |
| ▸ | MAG | P20916 | 10/20 | 0.51 |
| ▸ | SELP | P16109 | 2/20 | 0.47 |
| ▸ | SELL | P14151 | 1/20 | 0.47 |
| ▸ | NANP | Q8TBE9 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19820225 | 0.85 | MAG (0.53) | SIGLEC7MAGSELPSELL | |
| SCHEMBL25124455 | 0.83 | SELP (0.57) | SIGLEC7MAGSELPSELLNANP | |
| SCHEMBL14750464 | 0.80 | SIGLEC7 (0.55) | SIGLEC7MAGSELPSELLNANP | |
| SCHEMBL25124346 | 0.79 | MAG (0.53) | SIGLEC7MAGSELPSELL | |
| SCHEMBL25588781 | 0.78 | NANP (0.50) | SIGLEC7MAGSELPSELLNANP | |
| SCHEMBL19731797 | 0.77 | SIGLEC7 (0.38) | SIGLEC7MAGSELPSELL | |
| SCHEMBL14750348 | 0.76 | SELL (0.53) | SIGLEC7MAGSELPSELL | |
| SCHEMBL12682548 | 0.75 | SIGLEC7 (0.60) | SIGLEC7MAGSELPSELL | |
| SCHEMBL21064196 | 0.75 | SIGLEC7 (0.42) | SIGLEC7MAGSELPSELL | |
| SCHEMBL8472605 | 0.74 | NANP (0.58) | SIGLEC7MAGSELPSELLNANP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190209697-A1 | CELLS LABELLED WITH LIPID CONJUGATES AND METHODS OF USE THEREOF | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2019-07-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190209697-A1 | CELLS LABELLED WITH LIPID CONJUGATES AND METHODS OF USE THEREOF | NPC1L1, CETP, LIPA | SIGLEC7 53/4885MAG 503/4885SELP 115/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.