SCHEMBL2115368

SCHEMBL2115368

C[C@H](NC(=O)[C@H](N)CCCCN)C(=O)O

nearest known ligand 0.58

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
GSR P00390 1/20 0.58
DPP8 Q6V1X1 6/20 0.54
DPP9 Q86TI2 6/20 0.54
DPP7 Q9UHL4 5/20 0.54
GNAI3 P08754 1/20 0.50
GNAO1 P09471 1/20 0.50
GNAI1 P63096 1/20 0.50
DPP4 P27487 3/20 0.48
MMP2 P08253 1/20 0.43
RNPEP Q9H4A4 1/20 0.43
FOLH1 Q04609 1/20 0.41
SLC15A1 P46059 1/20 0.41
MME P08473 1/20 0.41
ACE P12821 1/20 0.41
CPA1 P15085 1/20 0.41
ACE2 Q9BYF1 1/20 0.41
THRB P10828 1/20 0.41
CPB2 Q96IY4 3/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17510190 1.00 GSR (0.58) GSRDPP8DPP9DPP7GNAI3
SCHEMBL2115366 1.00 GSR (0.58) GSRDPP8DPP9DPP7GNAI3
SCHEMBL19376936 1.00 GSR (0.58) GSRDPP8DPP9DPP7GNAI3
SCHEMBL7781619 1.00 GSR (0.58) GSRDPP8DPP9DPP7GNAI3
SCHEMBL1641741 1.00 GSR (0.58) GSRDPP8DPP9DPP7GNAI3
SCHEMBL9705058 1.00 GSR (0.58) GSRDPP8DPP9DPP7GNAI3
SCHEMBL1641744 1.00 GSR (0.58) GSRDPP8DPP9DPP7GNAI3
Hydrochloric Acid SCHEMBL8716381 0.98 GSR (0.56) GSRDPP8DPP9DPP7GNAI3
SCHEMBL1985169 0.97 GSR (0.55) GSRDPP8DPP9DPP7GNAI3
SCHEMBL10658822 0.97 GSR (0.55) GSRDPP8DPP9DPP7GNAI3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1323730-B1 NOVEL POLYPEPTIDES AND ANTI-HIV DRUGS CONTAINING THE SAME BIOKINE THERAPEUTICS LTD (IL) 2010-04-21 EP claimed
US-20100055088-A1 CXCR4 Antagonists for Wound Healing and Re-Epithelialization HADASIT MEDICAL RESEARCH SERVICES AND DEVELOPMENT LTD. (IL) 2010-03-04 US claimed
EP-1898943-A2 CXCR4 ANTAGONISTS FOR WOUND HEALING AND RE-EPITHELIALIZATION Hadasit Medical Research Services & Development Ltd. (IL) 2008-03-19 EP claimed
WO-2006126188-A2 CXCR4 ANTAGONISTS FOR WOUND HEALING AND RE-EPITHELIALIZATION HADASIT MEDICAL RESEARCH SERVICES AND DEVELOPMENT LTD. (IL) 2006-11-30 WO claimed
US-20040116655-A1 Novel polypeptides and anti-hiv drugs containing the same BIOKINE THERAPEUTICS LTD. (IL) 2004-06-17 US claimed
EP-1323730-A1 NOVEL POLYPEPTIDES AND ANTI-HIV DRUGS CONTAINING THE SAME SEIKAGAKU CORPORATION (JP) 2003-07-02 EP claimed
EP-4229211-A1 BINDING ASSAYS INVOLVING A PLURALITY OF SYNTHETIC COMPOUNDS, TARGETS, AND COUNTER TARGETS SRI International (US) 2023-08-23 EP disclosed
WO-2022082006-A1 BINDING ASSAYS INVOLVING A PLURALITY OF SYNTHETIC COMPOUNDS, TARGETS, AND COUNTER TARGETS SRI INTERNATIONAL (US) 2022-04-21 WO disclosed
EP-3011961-B1 4F-BENZOYL-TN14003 FOR THE MOBILISATION OF HEMATOPOIETIC PROGENITOR CELLS IN VIEW OF TRANSPLANTATION BIOKINE THERAPEUTICS LTD (IL) 2020-11-11 EP disclosed
EP-2841084-B1 CXCR4 ANTAGONIST PEPTIDE FOR USE IN THE TREATMENT OF LARGE CELL LUNG CANCER BIOKINE THERAPEUTICS LTD (IL) 2018-05-30 EP disclosed
US-9439942-B2 Peptides and use thereof in the treatment of large cell lung cancer BIOKINE THERAPEUTICS LTD. (IL) 2016-09-13 US disclosed
US-9427456-B2 Peptide therapy for increasing platelet levels BIOKINE THERAPEUTICS LTD. (IL) 2016-08-30 US disclosed
EP-3011961-A1 4F-benzoyl-TN14003 for the mobilisation of hematopoietic progenitor cells in view of transplantation Biokine Therapeutics LTD. (IL) 2016-04-27 EP disclosed
US-7138488-B2 Polypeptides having anti-HIV activity and compositions comprising same BIOKINE THERAPEUTICS LTD. (IL) 2006-11-21 US disclosed
US-20040116655-A1 Novel polypeptides and anti-hiv drugs containing the same BIOKINE THERAPEUTICS LTD. (IL) 2004-06-17 US disclosed
EP-1323730-A1 NOVEL POLYPEPTIDES AND ANTI-HIV DRUGS CONTAINING THE SAME SEIKAGAKU CORPORATION (JP) 2003-07-02 EP disclosed
US-6271342-B1 SERUM STABILITY; FOR TUMOR THERAPY BAYER AKTIENGESELLSCHAFT (DE) 2001-08-07 US disclosed
EP-0819135-B1 SUGAR-MODIFIED CYTOSTATICS BAYER AG (DE) 1999-11-17 EP disclosed
EP-0819135-A1 SUGAR-MODIFIED CYTOSTATICS BAYER AG (DE) 1998-01-21 EP disclosed
WO-1996031532-A1 SUGAR-MODIFIED CYTOSTATICS BAYER AKTIENGESELLSCHAFT (DE) 1996-10-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100055088-A1 CXCR4 Antagonists for Wound Healing and Re-Epithelialization CXCR4, CXCL12, CXCR5 GSR 4688/4885DPP8 2093/4885DPP9 2366/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.