Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XIAP | P98170 | 10/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | CASP9 | P55211 | 1/20 | 0.38 |
| ▸ | BIRC2 | Q13490 | 8/20 | 0.37 |
| ▸ | BIRC3 | Q13489 | 6/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | TNF | P01375 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2632125 | 1.00 | XIAP (0.40) | XIAPCYP3A4CYP2C9CYP2C19CASP9 | |
| SCHEMBL2113168 | 0.87 | XIAP (0.46) | XIAPCYP3A4CYP2C9CYP2C19CASP9 | |
| SCHEMBL2632123 | 0.87 | XIAP (0.46) | XIAPCYP3A4CYP2C9CYP2C19CASP9 | |
| SCHEMBL17577874 | 0.87 | XIAP (0.39) | XIAPCYP3A4CYP2C9CYP2C19CASP9 | |
| SCHEMBL2113474 | 0.87 | XIAP (0.41) | XIAPCYP3A4CYP2C9CYP2C19CASP9 | |
| SCHEMBL2632118 | 0.87 | XIAP (0.41) | XIAPCYP3A4CYP2C9CYP2C19CASP9 | |
| SCHEMBL2632085 | 0.86 | XIAP (0.44) | XIAPCASP9BIRC2BIRC3 | |
| SCHEMBL2114001 | 0.86 | XIAP (0.44) | XIAPCASP9BIRC2BIRC3 | |
| SCHEMBL2113660 | 0.86 | XIAP (0.40) | XIAPCYP3A4CYP2C9CYP2C19CASP9 | |
| SCHEMBL2632132 | 0.86 | XIAP (0.40) | XIAPCYP3A4CYP2C9CYP2C19CASP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120094917-A1 | IAP INHIBITORS | TETRALOGIC PHARMACEUTICALS CORP (US) | 2012-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120094917-A1 | IAP INHIBITORS | XIAP, IAPP, BIRC5 | XIAP 1/4885CYP3A4 3818/4885CYP2C9 4718/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.