Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EED | O75530 | 6/20 | 0.48 |
| ▸ | RBBP4 | Q09028 | 6/20 | 0.48 |
| ▸ | SUZ12 | Q15022 | 6/20 | 0.48 |
| ▸ | EZH2 | Q15910 | 6/20 | 0.48 |
| ▸ | AEBP2 | Q6ZN18 | 6/20 | 0.48 |
| ▸ | BAZ2B | Q9UIF8 | 3/20 | 0.43 |
| ▸ | BRD9 | Q9H8M2 | 3/20 | 0.43 |
| ▸ | KMO | O15229 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.40 |
| ▸ | POLQ | O75417 | 1/20 | 0.39 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.38 |
| ▸ | BRD7 | Q9NPI1 | 1/20 | 0.38 |
| ▸ | PIK3C2B | O00750 | 3/20 | 0.37 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.36 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.36 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29986315 | 1.00 | EED (0.48) | EEDRBBP4SUZ12EZH2AEBP2 | |
| SCHEMBL19964960 | 0.91 | EED (0.47) | EEDRBBP4SUZ12EZH2AEBP2 | |
| SCHEMBL21157366 | 0.90 | EED (0.46) | EEDRBBP4SUZ12EZH2AEBP2 | |
| SCHEMBL19964531 | 0.90 | EED (0.48) | EEDRBBP4SUZ12EZH2AEBP2 | |
| SCHEMBL21113256 | 0.86 | EED (0.44) | EEDRBBP4SUZ12EZH2AEBP2 | |
| SCHEMBL28958931 | 0.86 | EED (0.49) | EEDRBBP4SUZ12EZH2AEBP2 | |
| SCHEMBL28886578 | 0.86 | EED (0.43) | EEDRBBP4SUZ12EZH2AEBP2 | |
| SCHEMBL28886541 | 0.85 | EED (0.47) | EEDRBBP4SUZ12EZH2AEBP2 | |
| SCHEMBL28886549 | 0.85 | EED (0.48) | EEDRBBP4SUZ12EZH2AEBP2 | |
| SCHEMBL21157333 | 0.83 | EED (0.66) | EEDRBBP4SUZ12EZH2AEBP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109790160-B | Pyrido five-membered aromatic ring compound, preparation method and application thereof | 上海海和药物研究开发股份有限公司 | 2022-11-15 | — | — | CN | disclosed |
| US-10968215-B2 | Pyrido five-element aromatic ring compound, preparation method therefor and use thereof | SHANGHAI HAIHE PHARMACEUTICAL CO., LTD. (CN) | 2021-04-06 | — | — | US | disclosed |
| US-20190211010-A1 | PYRIDO FIVE-ELEMENT AROMATIC RING COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | HAIHE BIOPHARMA CO. LTD. (CN) | 2019-07-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10968215-B2 | Pyrido five-element aromatic ring compound, preparation method therefor and use thereof | EZH2, IKZF2, SUZ12 | EED 41/4885RBBP4 288/4885SUZ12 3/4885 |
| US-20190211010-A1 | PYRIDO FIVE-ELEMENT AROMATIC RING COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | EZH2, IKZF2, SUZ12 | EED 41/4885RBBP4 288/4885SUZ12 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.