Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2RL1 | P55085 | 7/20 | 0.76 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | PRCP | P42785 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | KIT | P10721 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.33 |
| ▸ | NAAA | Q02083 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16614824 | 0.90 | F2RL1 (0.82) | F2RL1HPGDKDM4EPRCPALDH1A1 | |
| SCHEMBL19637914 | 0.89 | F2RL1 (0.73) | F2RL1HPGDKDM4EPRCPALDH1A1 | |
| SCHEMBL16614720 | 0.88 | F2RL1 (0.79) | F2RL1HPGDKDM4EPRCPMAPT | |
| SCHEMBL16614576 | 0.88 | F2RL1 (0.79) | F2RL1HPGDKDM4EPRCPALDH1A1 | |
| SCHEMBL16598729 | 0.87 | F2RL1 (0.77) | F2RL1HPGDKDM4EALDH1A1MAPT | |
| SCHEMBL16614719 | 0.87 | F2RL1 (0.77) | F2RL1HPGDKDM4EKITABCG2 | |
| SCHEMBL16598394 | 0.87 | F2RL1 (1.00) | F2RL1HPGDKDM4EALDH1A1MAPT | |
| SCHEMBL16598572 | 0.87 | F2RL1 (0.77) | F2RL1HPGDKDM4EPRCPMAPT | |
| SCHEMBL16614511 | 0.87 | F2RL1 (0.77) | F2RL1HPGDKDM4EPRCPALDH1A1 | |
| SCHEMBL22758432 | 0.86 | F2RL1 (0.76) | F2RL1HPGDKDM4EMAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3508487-B1 | PYRAZOLO[1,5-A]PYRIMIDINE COMPOUND | EISAI R&D MAN CO LTD (JP) | 2021-06-16 | — | — | EP | disclosed |
| EP-3508487-A1 | PYRAZOLO[1,5-a]PYRIMIDINE COMPOUND | Eisai R&D Management Co., Ltd. (JP) | 2019-07-10 | — | — | EP | disclosed |