SCHEMBL211570

SCHEMBL211570

Nc1cc(Cl)c(Br)cn1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29637512 0.81
SCHEMBL4053901 0.81
SCHEMBL207537 0.77
SCHEMBL29739386 0.77
SCHEMBL20772455 0.77
SCHEMBL29849906 0.77
SCHEMBL19532041 0.77 PDPK1 (0.44)
SCHEMBL29567534 0.77 PDPK1 (0.44)
SCHEMBL191637 0.75
SCHEMBL13016652 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 375 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112867716-A Solid forms of FGFR inhibitors and methods for their preparation 因赛特公司 2021-05-28 CN claimed
EP-3788047-A2 SOLID FORMS OF AN FGFR INHIBITOR AND PROCESSES FOR PREPARING THE SAME Incyte Corporation (US) 2021-03-10 EP claimed
US-20190337948-A1 SOLID FORMS OF AN FGFR INHIBITOR AND PROCESSES FOR PREPARING THE SAME WILMINGTON PHARMATECH 2019-11-07 US claimed
WO-2015157360-A1 PROCESSES TO MAKE PROTEIN KINASE INHIBITORS ABBVIE INC. (US) 2015-10-15 WO claimed
US-20260137706-A1 METHODS OF TREATING INFLAMMATORY DISEASES INTERLINE THERAPEUTICS INC (US) 2026-05-21 US disclosed
WO-2026090330-A1 COMPOUNDS AND USES THEREOF FOGHORN THERAPEUTICS INC. (US) 2026-04-30 WO disclosed
EP-4121423-B1 TETRAZOLE DERIVATIVES MERCK PATENT GMBH (DE) 2026-04-29 EP disclosed
US-20260108521-A1 GSPT1 DEGRADERS, COMPOSITIONS COMPRISING THE DEGRADER, AND METHODS OF USING THE SAME BIOFRONT LTD (KY) 2026-04-23 US disclosed
EP-4724440-A1 METHODS OF TREATING INFLAMMATORY DISEASES Interline Therapeutics, Inc. (US) 2026-04-15 EP disclosed
EP-4702021-A1 COMPOUNDS CAPABLE OF MODULATING GPR65 Pathios Therapeutics Limited (GB) 2026-03-04 EP disclosed
US-12552792-B2 Solid forms of an FGFR inhibitor and processes for preparing the same INCYTE CORPORATION (US) 2026-02-17 US disclosed
EP-4665453-A1 GPR65 MODULATORS Pathios Therapeutics Limited (GB) 2025-12-24 EP disclosed
US-20090247507-A1 Enzyme Inhibitors THE INSTITUTE OF CANCER RESEARCH (GB) 2009-10-01 US disclosed
CN-101389622-A Pyrimidine derivatives used as pi-3 kinase inhibitors NOVARTIS AG (CH) 2009-03-18 CN disclosed
EP-1984350-A1 PYRIMIDINE DERIVATIVES USED AS PI-3 KINASE INHIBITORS Novartis AG (CH) 2008-10-29 EP disclosed
EP-1963315-A2 ENZYME INHIBITORS The Institute of Cancer Research (GB) 2008-09-03 EP disclosed
WO-2007084786-A1 PYRIMIDINE DERIVATIVES USED AS PI-3 KINASE INHIBITORS NOVARTIS AG (CH) 2007-07-26 WO disclosed
WO-2007084786-A1 PYRIMIDINE DERIVATIVES USED AS PI-3 KINASE INHIBITORS NOVARTIS AG (CH) 2007-07-26 WO disclosed
WO-2007072017-A2 ENZYME INHIBITORS THE INSTITUTE OF CANCER RESEARCH (GB) 2007-06-28 WO disclosed
WO-2007072017-A2 ENZYME INHIBITORS THE INSTITUTE OF CANCER RESEARCH (GB) 2007-06-28 WO disclosed