Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.30 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.30 |
| ▸ | CTSK | P43235 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL212446 | 1.00 | ABL1 (0.31) | ABL1CARM1PRMT6CTSK | |
| SCHEMBL210282 | 0.99 | ABL1 (0.32) | ABL1CARM1PRMT6CTSK | |
| SCHEMBL210286 | 0.99 | ABL1 (0.32) | ABL1CARM1PRMT6CTSK | |
| SCHEMBL210742 | 0.93 | ABL1 (0.30) | ABL1 | |
| SCHEMBL211897 | 0.93 | ABL1 (0.30) | ABL1 | |
| SCHEMBL211246 | 0.92 | ABL1 (0.30) | ABL1 | |
| SCHEMBL210106 | 0.92 | ABL1 (0.30) | ABL1 | |
| SCHEMBL212248 | 0.91 | ABL1 (0.31) | ABL1 | |
| SCHEMBL213879 | 0.91 | ABL1 (0.31) | ABL1 | |
| SCHEMBL9608011 | 0.90 | EGFR (0.32) | ABL1CARM1PRMT6CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8088793-B2 | Certain chemical entities, compositions, and methods | CYTOKINETICS, INC. (US) | 2012-01-03 | — | — | US | disclosed |