SCHEMBL21159906

SCHEMBL21159906

C/C=C\c1cccc(-c2ccc3ccc(-c4ccc(-c5nc(-c6ccccc6)nc(-c6ccccc6)n5)cc4)cc3c2)c1N

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BACE1 P56817 4/20 0.40
MEN1 O00255 5/20 0.38
KMT2A Q03164 5/20 0.38
ALDH1A1 P00352 3/20 0.38
MAPT P10636 2/20 0.38
HPGD P15428 2/20 0.38
KDM4E B2RXH2 2/20 0.37
LMNA P02545 1/20 0.37
GLA P06280 1/20 0.37
ESR1 P03372 1/20 0.36
ESR2 Q92731 1/20 0.36
CTSD P07339 1/20 0.36
ADORA2A P29274 4/20 0.35
ADORA1 P30542 4/20 0.35
ADORA3 P0DMS8 2/20 0.35
ADORA2B P29275 2/20 0.35
ALOX15 P16050 1/20 0.35
TSHR P16473 1/20 0.35
HTT P42858 1/20 0.34
POLB P06746 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21159674 0.96 BACE1 (0.39) BACE1MEN1KMT2AALDH1A1MAPT
SCHEMBL21160151 0.84 MEN1 (0.36) MEN1KMT2AALDH1A1MAPTHPGD
SCHEMBL21132114 0.82 ESR1 (0.34) BACE1MEN1KMT2AALDH1A1MAPT
SCHEMBL22056878 0.81 ADORA2A (0.38) MEN1KMT2AALDH1A1MAPTHPGD
SCHEMBL21159673 0.80 MEN1 (0.40) BACE1MEN1KMT2AALDH1A1MAPT
SCHEMBL22809222 0.79 TSHR (0.35) MEN1KMT2AALDH1A1MAPTHPGD
SCHEMBL21160166 0.78 TSHR (0.36) MEN1KMT2AALDH1A1MAPTHPGD
SCHEMBL27364571 0.73 SRC (0.43) BACE1MEN1KMT2AALDH1A1MAPT
SCHEMBL15850715 0.73 ESR1 (0.61) BACE1MEN1KMT2AALDH1A1MAPT
SCHEMBL17655916 0.73 ESR1 (0.61) BACE1MEN1KMT2AALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3498804-B1 ORGANIC LIGHT EMITTING DEVICE LG CHEMICAL LTD (KR) 2020-06-03 EP disclosed
EP-3498804-A1 ORGANIC LIGHT EMITTING DEVICE LG Chem, Ltd. (KR) 2019-06-19 EP disclosed