Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKDC | P78527 | 4/20 | 0.67 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.57 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.57 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.57 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.48 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.42 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21155632 | 0.86 | PRKDC (0.62) | PRKDCPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL5063514 | 0.85 | PRKDC (0.72) | PRKDCPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL7090207 | 0.85 | PRKDC (0.71) | PRKDCPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL5063516 | 0.85 | PRKDC (0.71) | PRKDCPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL3216387 | 0.82 | PRKDC (0.68) | PRKDCPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL5054826 | 0.82 | PRKDC (0.72) | PRKDCPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL5065314 | 0.82 | PRKDC (0.68) | PRKDCPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL5058593 | 0.82 | PRKDC (0.67) | PRKDCPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL5058436 | 0.81 | PRKDC (0.66) | PRKDCPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL5054910 | 0.81 | PRKDC (0.65) | PRKDCPIK3CDPIK3CAPIK3CBPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019136298-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS FOR TREATMENT OF DISEASES INVOLVING ACIDIC OR HYPOXIC DISEASED TISSUES | Cybrexa, Inc. (US) | 2019-07-11 | — | — | WO | disclosed |