⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30360459 | 1.00 | — | — | |
| SCHEMBL342957 | 0.82 | — | — | |
| SCHEMBL30706761 | 0.82 | — | — | |
| SCHEMBL1459949 | 0.79 | — | — | |
| SCHEMBL29546988 | 0.78 | HTT (0.50) | — | |
| SCHEMBL20043 | 0.78 | HTT (0.50) | — | |
| SCHEMBL1043573 | 0.77 | — | — | |
| SCHEMBL31133690 | 0.76 | HTT (0.48) | — | |
| SCHEMBL23704250 | 0.76 | CYP2A6 (0.59) | — | |
| SCHEMBL15334774 | 0.75 | TSHR (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 582 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115605466-B | Substituted oxoisoindoline compounds for the treatment of cancer | 百时美施贵宝公司 | 2024-11-01 | — | — | CN | claimed |
| CN-110139862-B | Substituted bicyclic heterocyclic derivatives useful as ROMK channel inhibitors | 百时美施贵宝公司 | 2024-01-16 | — | — | CN | claimed |
| CN-117199519-A | Electrolyte, preparation method and application thereof, and lithium battery | 北京纳米能源与系统研究所 | 2023-12-08 | — | — | CN | claimed |
| CN-117157286-A | Pyridyl-substituted oxo-isoindoline compounds | 百时美施贵宝公司 | 2023-12-01 | — | — | CN | claimed |
| CN-110678463-B | Substituted nitrogen-containing compounds | 百时美施贵宝公司 | 2023-06-06 | — | — | CN | claimed |
| EP-3330270-B1 | PYRIDOPHENANTHROLINE DERIVATIVE, ITS PRODUCTION AND UTILISATION AS MEDICINE | UNIV KIEL CHRISTIAN ALBRECHTS (DE) | 2023-04-05 | — | — | EP | claimed |
| CN-115605466-A | Substituted oxoisoindoline compounds for the treatment of cancer | 百时美施贵宝公司（US） | 2023-01-13 | — | — | CN | claimed |
| CN-111153825-A | Method for preparing amide compound by using supported metal oxide catalytic material | 浙江大学 | 2020-05-15 | — | — | CN | claimed |
| CN-106632301-B | Synthesis method of pyridine-bis-thiazole carboxylic acid derivative | 云南大学 | 2020-03-17 | — | — | CN | claimed |
| US-20190292184-A1 | NOVEL PYRIDO-PHENANTHROLINE DERIVATIVES, PRODUCTION AND USE THEREOF AS MEDICAMENTS | CHRISTIAN-ALBRECHTS-UNIVERSITAT ZU KIEL (DE) | 2019-09-26 | — | — | US | claimed |
| WO-2007107345-A2 | PROCESS FOR PREPARING l-HALO-2,7-NAPHTHYRIDINYL DERIVATIVES | UCB PHARMA, S.A. (BE) | 2007-09-27 | — | — | WO | claimed |
| US-20050234108-A1 | 8-[3-amino-piperidin-1-yl]-xanthines, their preparation and their use as pharmaceutical compositions | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2005-10-20 | — | — | US | claimed |
| US-20050187227-A1 | 8-[3-Amino-piperidin-1-yl]-xanthines, their preparation and their use as pharmaceutical composition | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2005-08-25 | — | — | US | claimed |
| EP-1399438-A1 | NOVEL HETEROARYL DERIVATIVES, THEIR PREPARATION AND USE | H. Lundbeck A/S (DK) | 2004-03-24 | — | — | EP | claimed |
| WO-2003002556-A1 | NOVEL HETEROARYL DERIVATIVES, THEIR PREPARATION AND USE | H. LUNDBECK A/S (DK) | 2003-01-09 | — | — | WO | claimed |
| US-5668287-A | Method for the preparation of 3-amino-2-chloro-4-methylpyridines | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 1997-09-16 | — | — | US | claimed |
| EP-0551459-B1 | METHOD FOR THE PREPARATION OF 3-AMINO-2-CHLORO-4-ALKYLPYRIDINES | BOEHRINGER INGELHEIM PHARMA (US) | 1996-11-20 | — | — | EP | claimed |
| EP-0551459-A4 | — | — | 1994-03-16 | — | — | EP | claimed |
| EP-0551459-A1 | METHOD FOR THE PREPARATION OF 3-AMINO-2-CHLORO-4-ALKYLPYRIDINES. | BOEHRINGER INGELHEIM PHARMA (US) | 1993-07-21 | — | — | EP | claimed |
| WO-1992022531-A1 | METHOD FOR THE PREPARATION OF 3-AMINO-2-CHLORO-4-ALKYLPYRIDINES | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 1992-12-23 | — | — | WO | claimed |