Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CFTR | P13569 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2742862 | 0.82 | SMN1; SMN2 (0.41) | SMN1; SMN2LMNAL3MBTL1CFTRSLC6A2 | |
| SCHEMBL21162240 | 0.80 | SMN1; SMN2 (0.39) | SMN1; SMN2LMNAL3MBTL1CFTRSLC6A2 | |
| SCHEMBL7043773 | 0.79 | CFTR (0.44) | SMN1; SMN2LMNAL3MBTL1CFTRSLC6A2 | |
| SCHEMBL27745528 | 0.79 | CFTR (0.44) | SMN1; SMN2LMNAL3MBTL1CFTRSLC6A2 | |
| SCHEMBL22113733 | 0.78 | NPC1 (0.53) | SMN1; SMN2LMNAL3MBTL1CFTRSLC6A2 | |
| SCHEMBL14233502 | 0.78 | NPC1 (0.53) | SMN1; SMN2LMNAL3MBTL1CFTRSLC6A2 | |
| SCHEMBL1245510 | 0.78 | NPC1 (0.53) | SMN1; SMN2LMNAL3MBTL1CFTRSLC6A2 | |
| SCHEMBL10644871 | 0.78 | TAAR1 (0.48) | LMNA | |
| SCHEMBL10644867 | 0.78 | TAAR1 (0.48) | LMNA | |
| SCHEMBL28744344 | 0.78 | SMN1; SMN2 (0.43) | SMN1; SMN2LMNAL3MBTL1CFTRSLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3898607-B1 | 3-(1,2,3,6-TETRAHYDROPYRIDIN-2-YL)PYRIDINE GLUTARATE OR A PHARMACEUTICALLY ACCEPTABLE SOLVATE THEREOF | PHILIP MORRIS PRODUCTS SA (CH) | 2023-10-18 | — | — | EP | disclosed |
| US-20190203218-A1 | METHOD | NORTH CAROLINA STATE UNIVERSITY | 2019-07-04 | — | — | US | disclosed |