Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 11/20 | 0.66 |
| ▸ | NOD1 | Q9Y239 | 4/20 | 0.48 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.44 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.44 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.42 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.42 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.42 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19633812 | 0.94 | FOLH1 (0.66) | FOLH1NOD1RIMKLANAALAD2PLA2G2C | |
| SCHEMBL17246764 | 0.86 | FOLH1 (0.64) | FOLH1RIMKLANAALAD2SLC6A5 | |
| SCHEMBL12349358 | 0.83 | FOLH1 (0.55) | FOLH1NOD1RIMKLANAALAD2PLA2G2C | |
| SCHEMBL22539941 | 0.83 | FOLH1 (0.55) | FOLH1NOD1RIMKLANAALAD2PLA2G2C | |
| SCHEMBL19611478 | 0.80 | FOLH1 (0.64) | FOLH1RIMKLANAALAD2 | |
| SCHEMBL19611476 | 0.80 | FOLH1 (0.64) | FOLH1RIMKLANAALAD2 | |
| SCHEMBL19611479 | 0.80 | FOLH1 (0.64) | FOLH1RIMKLANAALAD2 | |
| SCHEMBL25360880 | 0.79 | FOLH1 (1.00) | FOLH1RIMKLANAALAD2 | |
| SCHEMBL25360876 | 0.79 | FOLH1 (1.00) | FOLH1RIMKLANAALAD2 | |
| SCHEMBL19633801 | 0.79 | FOLH1 (0.57) | FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3140282-B1 | METAL/RADIOMETAL-LABELED PSMA INHIBITORS FOR PSMA-TARGETED IMAGING AND RADIOTHERAPY | UNIV JOHNS HOPKINS (US) | 2019-07-10 | — | — | EP | disclosed |