Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | ENPP1 | P22413 | 3/20 | 0.53 |
| ▸ | P2RY1 | P47900 | 2/20 | 0.53 |
| ▸ | AHCY | P23526 | 1/20 | 0.47 |
| ▸ | DOT1L | Q8TEK3 | 4/20 | 0.45 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.45 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.45 |
| ▸ | DTYMK | P23919 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22348794 | 1.00 | POLB (0.54) | POLBENPP1P2RY1AHCYDOT1L | |
| SCHEMBL22348799 | 1.00 | POLB (0.54) | POLBENPP1P2RY1AHCYDOT1L | |
| SCHEMBL22348864 | 0.95 | POLB (0.51) | POLBENPP1P2RY1AHCYDOT1L | |
| SCHEMBL22348862 | 0.95 | POLB (0.51) | POLBENPP1P2RY1AHCYDOT1L | |
| SCHEMBL21162568 | 0.95 | POLB (0.51) | POLBENPP1P2RY1AHCYDOT1L | |
| SCHEMBL23187796 | 0.93 | POLB (0.56) | POLBENPP1P2RY1P2RY12P2RY2 | |
| SCHEMBL22348860 | 0.93 | POLB (0.56) | POLBENPP1P2RY1P2RY12P2RY2 | |
| SCHEMBL19821278 | 0.92 | POLB (0.54) | POLBENPP1P2RY1P2RY2DTYMK | |
| SCHEMBL19821262 | 0.92 | POLB (0.54) | POLBENPP1P2RY1P2RY2DTYMK | |
| SCHEMBL21162567 | 0.92 | POLB (0.55) | POLBENPP1P2RY1DTYMK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019136389-A1 | NUCLEOTIDE PRODRUGS | CERECOR, INC. (US) | 2019-07-11 | — | — | WO | disclosed |