Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | P2RY2 | P41231 | 3/20 | 0.46 |
| ▸ | P2RY4 | P51582 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | P2RY6 | Q15077 | 2/20 | 0.46 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.44 |
| ▸ | TYMS | P04818 | 1/20 | 0.43 |
| ▸ | ST6GAL1 | P15907 | 3/20 | 0.42 |
| ▸ | NT5E | P21589 | 1/20 | 0.42 |
| ▸ | DUT | P33316 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18714594 | 1.00 | POLB (0.53) | POLBP2RY2P2RY4CYP3A4CYP2C9 | |
| SCHEMBL22348832 | 1.00 | POLB (0.53) | POLBP2RY2P2RY4CYP3A4CYP2C9 | |
| SCHEMBL19227905 | 1.00 | POLB (0.53) | POLBP2RY2P2RY4CYP3A4CYP2C9 | |
| SCHEMBL22348866 | 0.95 | POLB (0.50) | POLBP2RY2P2RY4CYP3A4CYP2C9 | |
| SCHEMBL22348867 | 0.95 | POLB (0.50) | POLBP2RY2P2RY4CYP3A4CYP2C9 | |
| SCHEMBL22348842 | 0.93 | POLB (0.55) | POLBP2RY2P2RY4CYP3A4CYP2C9 | |
| SCHEMBL22348843 | 0.93 | POLB (0.55) | POLBP2RY2P2RY4CYP3A4CYP2C9 | |
| SCHEMBL19831365 | 0.92 | POLB (0.53) | POLBP2RY2P2RY4CYP3A4CYP2C9 | |
| SCHEMBL19821229 | 0.92 | POLB (0.53) | POLBP2RY2P2RY4CYP3A4CYP2C9 | |
| SCHEMBL23104998 | 0.92 | CYP3A4 (0.55) | POLBP2RY2P2RY4CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019136389-A1 | NUCLEOTIDE PRODRUGS | CERECOR, INC. (US) | 2019-07-11 | — | — | WO | disclosed |