SCHEMBL211632

SCHEMBL211632

Cl[Pd]Cl.c1ccc(P(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.75

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.75
TDP1 Q9NUW8 1/20 0.75
ESR1 P03372 4/20 0.55
ESR2 Q92731 4/20 0.55
KDM4E B2RXH2 1/20 0.42
GAA P10253 1/20 0.42
TSHR P16473 4/20 0.35
NPSR1 Q6W5P4 1/20 0.33
APP P05067 1/20 0.33
DRD1 P21728 2/20 0.32
LMNA P02545 2/20 0.32
ALDH1A1 P00352 1/20 0.32
HPGD P15428 1/20 0.32
HTT P42858 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
BBOX1 O75936 1/20 0.30
EHMT2 Q96KQ7 1/20 0.30
EHMT1 Q9H9B1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4055738 1.00 CYP3A4 (0.75) CYP3A4TDP1ESR1ESR2KDM4E
SCHEMBL1823 1.00 CYP3A4 (0.75) CYP3A4TDP1ESR1ESR2KDM4E
SCHEMBL5598857 1.00 CYP3A4 (0.75) CYP3A4TDP1ESR1ESR2KDM4E
SCHEMBL30067172 0.97 CYP3A4 (0.71) CYP3A4TDP1ESR1ESR2KDM4E
SCHEMBL30041418 0.97 CYP3A4 (0.71) CYP3A4TDP1ESR1ESR2KDM4E
Hydrochloric Acid SCHEMBL7233266 0.97 CYP3A4 (0.71) CYP3A4TDP1ESR1ESR2KDM4E
SCHEMBL6415873 0.97 CYP3A4 (0.71) CYP3A4TDP1ESR1ESR2KDM4E
Methane SCHEMBL28585682 0.97 CYP3A4 (0.71) CYP3A4TDP1ESR1ESR2KDM4E
SCHEMBL2653270 0.97 CYP3A4 (0.71) CYP3A4TDP1ESR1ESR2KDM4E
SCHEMBL29359632 0.97 CYP3A4 (0.71) CYP3A4TDP1ESR1ESR2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 5134 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117209435-B Method for preparing 2, 6-dimethoxy-4-aminopyrimidine through micro-channel 浙江海昇药业股份有限公司 2026-05-12 CN claimed
CN-116410118-B Preparation method of beta-lactam compound 中国科学技术大学 2025-06-24 CN claimed
CN-120081813-A Two-photon initiator, preparation method and application 西安江大微纳材料科技有限公司 2025-06-03 CN claimed
CN-120081782-A Preparation method of 2-aminoethyl-3-chloro-5-trifluoromethylpyridine 天津均凯农业科技有限公司 2025-06-03 CN claimed
WO-2025081982-A1 PREPARATION METHOD FOR FINERENONE KEY INTERMEDIATE 山东诚创蓝海医药科技有限公司 2025-04-24 WO claimed
CN-119859112-A Preparation method of non-neridrone key intermediate 山东诚创蓝海医药科技有限公司 2025-04-22 CN claimed
WO-2025073270-A1 BIPHENYL TETRAHYDROPYRROLE COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF 海南因瑞生物医药科技有限公司 2025-04-10 WO claimed
CN-119751445-A Preparation method of 6-ethynyl pyrazolo [1,5-a ] pyridine 江南大学 2025-04-04 CN claimed
CN-119613699-A Method for removing perfluoro polyether acyl fluoride end group 南开大学 2025-03-14 CN claimed
CN-119591501-A Synthesis method of fluorine-containing biphenyl compound by one-pot method 江苏广域化学有限公司 2025-03-11 CN claimed
US-6498271-B2 BIOTRANSFORMATION OF AN OLEFINIC MONOCARBOXYLIC ACID (OLEIC ACID) TO THE 1,18-OCTADEC-9-ENEDIOIC ACID IN PRESENCE OF CANDIDA TROPICALIS, A YEAST STRAIN, FOLLOWED BY CARBOXYLATON OF INTERMEDIATE BY REACTION WITH CARBON MONOXIDE AND WATER GENERAL ELECTRIC COMPANY 2002-12-24 US claimed
US-20020169339-A1 Tricarboxylic acids, method, and branched polycarbonates prepared therefrom SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2002-11-14 US claimed
CN-1253558-A Substituted imidazoles useful in treatment of inflammatory diseases ORTHO MCNEIL CORP INC (US) 2000-05-17 CN claimed
CN-1171101-A Process for preparation of aromatic 0-sulfocarboxylic acids and sulfonylureas CIBA GEIGY AG (CH) 1998-01-21 CN claimed
US-5567851-A Cyclohexene diol derivatives CHISSO CORPORATION (JP) 1996-10-22 US claimed
CN-1108659-A Trifluoroisopropenyl zinc reagent and its derivate application SHANGHAI INST ORGANIC CHEM (CN) 1995-09-20 CN claimed
CN-1029679-C Method for producing ibuprofen HOECHST CELANESE CORP (US) 1995-09-06 CN claimed
CN-1051911-A Trifluoroisopropenyl zinc reagent and derivative, preparation and application thereof SHANGHAI ORGANIC CHEMESTRY INS (CN) 1991-06-05 CN claimed
US-4956507-A GRIGNARD REAGENTS FROM P-HALOFLUOROBENZENE AND MAGNESIUM COUPLING TO FORM P,P*-DIFLUOROBIPHENYL PHILLIPS PETROLEUM COMPANY (US) 1990-09-11 US claimed
CN-88102150-A METHOD FOR PRODUCING IBUPROFEN 1988-11-23 CN claimed