Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 4/20 | 0.40 |
| ▸ | CA2 | P00918 | 4/20 | 0.40 |
| ▸ | CA12 | O43570 | 3/20 | 0.40 |
| ▸ | CA9 | Q16790 | 3/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.39 |
| ▸ | HTR1A | P08908 | 2/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 2/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | SDCBP | O00560 | 1/20 | 0.37 |
| ▸ | SDC2 | P34741 | 1/20 | 0.37 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26346279 | 0.86 | MEN1 (0.50) | MEN1KMT2AGAATDP1CA1 | |
| SCHEMBL14642562 | 0.84 | TDP1 (0.47) | MEN1KMT2AGAATDP1CA1 | |
| SCHEMBL15987190 | 0.83 | TDP1 (0.46) | MEN1KMT2AGAATDP1CA1 | |
| SCHEMBL13055393 | 0.82 | TDP1 (0.58) | MEN1KMT2AGAATDP1CA1 | |
| SCHEMBL9355239 | 0.82 | TDP1 (0.57) | MEN1KMT2AGAATDP1CA1 | |
| SCHEMBL25281589 | 0.82 | MEN1 (0.43) | MEN1KMT2AGAATDP1CA1 | |
| SCHEMBL25835271 | 0.81 | TDP1 (0.44) | MEN1KMT2AGAATDP1CA1 | |
| SCHEMBL25886688 | 0.81 | CAPN1 (0.45) | MEN1KMT2AGAATDP1CA1 | |
| SCHEMBL22276648 | 0.81 | TDP1 (0.56) | MEN1KMT2AGAATDP1CA1 | |
| SCHEMBL12885084 | 0.81 | TDP1 (0.56) | MEN1KMT2AGAATDP1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10352941-B2 | Method for functionalizing a porous membrane covering of an optical sensor to facilitate coupling of an antithrom-bogenic agent | MEDTRONIC MINIMED, INC. (US) | 2019-07-16 | — | — | US | disclosed |