⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL683343 | 0.80 | — | — | |
| SCHEMBL9371348 | 0.76 | — | — | |
| SCHEMBL14157628 | 0.76 | — | — | |
| SCHEMBL14152113 | 0.76 | — | — | |
| SCHEMBL85641 | 0.76 | CNR2 (0.30) | — | |
| SCHEMBL3377554 | 0.76 | — | — | |
| SCHEMBL24615096 | 0.76 | — | — | |
| SCHEMBL10280220 | 0.74 | HRH3 (0.31) | — | |
| SCHEMBL2629431 | 0.73 | — | — | |
| SCHEMBL31582646 | 0.72 | CNR2 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210163455-A1 | GLP-1 Receptor Agonists and Uses Thereof | PFIZER INC. (US) | 2021-06-03 | — | — | US | disclosed |
| US-10392422-B2 | Macrocyclic broad spectrum antibiotics | RQX PHARMACEUTICALS, INC. (US) | 2019-08-27 | — | — | US | disclosed |
| US-10351595-B2 | — | — | 2019-07-16 | — | — | US | disclosed |