SCHEMBL2116759

SCHEMBL2116759

Cc1ncc(N)c(C)n1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL788493 0.79
SCHEMBL19313257 0.79
SCHEMBL28352277 0.75
SCHEMBL30193964 0.75
SCHEMBL10996697 0.75
SCHEMBL6551835 0.75
SCHEMBL4643246 0.75
SCHEMBL3844557 0.75
SCHEMBL18612796 0.75
SCHEMBL130245 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 114 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118164918-A Synthesis method of 2, 4-dimethyl-5-aminopyrimidine 南通大学 2024-06-11 CN claimed
EP-3558310-B1 HETEROARYL PIPERIDINE ETHER ALLOSTERIC MODULATORS OF THE M4 MUSCARINIC ACETYLCHOLINE RECEPTOR MERCK SHARP & DOHME LLC (US) 2024-01-17 EP claimed
CN-109071488-B Substituted 1,2, 3-triazoles as NR 2B-selective NMDA modulators 詹森药业有限公司 2021-08-13 CN claimed
CN-110759868-A Preparation method of rosuvastatin 雅本化学股份有限公司 2020-02-07 CN claimed
CN-109071488-A Substituted 1,2,3- triazole is as NR2B- selective NMDA regulator 詹森药业有限公司 2018-12-21 CN claimed
EP-2685821-A1 NUCLEAR HORMONE RECEPTOR MODULATORS AbbVie Inc. (US) 2014-01-22 EP claimed
US-20120238549-A1 Nuclear Hormone Receptor Modulators ABBOTT LABORATORIES (US) 2012-09-20 US claimed
WO-2012125797-A1 NUCLEAR HORMONE RECEPTOR MODULATORS ABBOTT LABORATORIES (US) 2012-09-20 WO claimed
CN-102311457-A Preparation method of rosuvastatin SUZHOU LAKESTAR PHARMATECH CO LTD 2012-01-11 CN claimed
CN-1419450-A Nitrate salts of antimicrobial drugs NICOX SA (FR) 2003-05-21 CN claimed
WO-2025215153-A1 PRMT5 INHIBITORS Ryvu Therapeutics S.A. (PL) 2025-10-16 WO disclosed
US-20250270209-A1 LRRK2 INHIBITORS INTERLINE THERAPEUTICS, INC. 2025-08-28 US disclosed
EP-4522616-A1 LRRK2 INHIBITORS Interline Therapeutics, Inc. (US) 2025-03-19 EP disclosed
CN-119403801-A LRRK2 inhibitors 因特来治疗公司 2025-02-07 CN disclosed
CN-118164918-A Synthesis method of 2, 4-dimethyl-5-aminopyrimidine 南通大学 2024-06-11 CN disclosed
WO-2002026752-A1 α-SUBSTITUTED β-AMINOETHYL PHOSPHONATES ILEX ONCOLOGY RESEARCH S.A. (CH) 2002-04-04 WO disclosed
US-5969077-A Polysiloxanes containing heterocyclic functions, their preparation and use WACKER-CHEMIE GMBH (DE) 1999-10-19 US disclosed
EP-0906930-A1 Polysiloxanes with heterocyclic functions, their preparation and use Wacker-Chemie GmbH (DE) 1999-04-07 EP disclosed
US-5776858-A HERBICIDES NIHON BAYER AGROCHEM K.K. (JP) 1998-07-07 US disclosed
EP-0771797-A1 1-Azinyl-tetrazolinone herbicides NIHON BAYER AGROCHEM K.K. (JP) 1997-05-07 EP disclosed