Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK10 | P53779 | 3/20 | 0.35 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.33 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15860052 | 0.97 | MAPK10 (0.34) | MAPK10MAPK9NR3C1CYP1A2SMN1; SMN2 | |
| SCHEMBL24361384 | 0.95 | MEN1 (0.36) | MAPK10MAPK9NR3C1CYP1A2SMN1; SMN2 | |
| SCHEMBL24361382 | 0.93 | MEN1 (0.35) | MAPK10MAPK9NR3C1CYP1A2SMN1; SMN2 | |
| SCHEMBL15860077 | 0.93 | AVPR1A (0.35) | NR3C1CYP1A2SMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL21863077 | 0.93 | AVPR1A (0.35) | NR3C1CYP1A2SMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL22479854 | 0.92 | GAA (0.34) | SMN1; SMN2MEN1ALDH1A1KMT2ACYP1A1 | |
| SCHEMBL24157140 | 0.92 | MEN1 (0.37) | CYP1A2SMN1; SMN2MEN1ALDH1A1KMT2A | |
| SCHEMBL19266724 | 0.91 | PDPK1 (0.35) | NR3C1CYP1A2SMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL19428964 | 0.91 | KDM4E (0.36) | MAPK10MAPK9NR3C1CYP1A2SMN1; SMN2 | |
| SCHEMBL24361472 | 0.91 | KDM4E (0.37) | NR3C1CYP1A2SMN1; SMN2MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190221751-A1 | ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING AN ELECTRON BUFFER LAYER AND AN ELECTRON TRANSPORT LAYER | DUPONT SPECIALTY MATERIALS KOREA LTD (KR) | 2019-07-18 | — | — | US | disclosed |