Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.52 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.45 |
| ▸ | CACNG8 | Q8WXS5 | 1/20 | 0.45 |
| ▸ | CACNG2 | Q9Y698 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21127973 | 0.99 | ESR1 (0.53) | ESR1ESR2MEN1KMT2AMAPT | |
| SCHEMBL21167844 | 0.96 | ESR1 (0.48) | ESR1ESR2MEN1KMT2AMAPT | |
| SCHEMBL19369614 | 0.90 | ESR1 (0.54) | ESR1ESR2MEN1KMT2AMAPT | |
| SCHEMBL20032208 | 0.90 | ESR1 (0.54) | ESR1ESR2MEN1KMT2AMAPT | |
| SCHEMBL16604614 | 0.89 | ESR1 (0.49) | ESR1ESR2MEN1KMT2AMAPT | |
| SCHEMBL19369613 | 0.89 | ESR1 (0.56) | ESR1ESR2MEN1KMT2AMAPT | |
| SCHEMBL19397515 | 0.88 | ESR1 (0.47) | ESR1ESR2MEN1KMT2AMAPT | |
| SCHEMBL19397628 | 0.88 | ESR1 (0.47) | ESR1ESR2MEN1KMT2AMAPT | |
| SCHEMBL24952476 | 0.87 | ESR1 (0.52) | ESR1ESR2MEN1KMT2AMAPT | |
| SCHEMBL19369622 | 0.87 | ESR1 (0.49) | ESR1ESR2MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190221751-A1 | ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING AN ELECTRON BUFFER LAYER AND AN ELECTRON TRANSPORT LAYER | DUPONT SPECIALTY MATERIALS KOREA LTD (KR) | 2019-07-18 | — | — | US | disclosed |