Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.71 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.71 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 4/20 | 0.42 |
| ▸ | PPARA | Q07869 | 4/20 | 0.42 |
| ▸ | TERT | O14746 | 3/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.42 |
| ▸ | PPARD | Q03181 | 3/20 | 0.42 |
| ▸ | BLM | P54132 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | FABP4 | P15090 | 2/20 | 0.42 |
| ▸ | F7 | P08709 | 2/20 | 0.42 |
| ▸ | F3 | P13726 | 2/20 | 0.42 |
| ▸ | GMNN | O75496 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16412283 | 1.00 | MAPT (0.71) | MAPTABCC4LMNAALDH1A1TSHR | |
| SCHEMBL27039983 | 0.91 | MAPT (0.54) | MAPTABCC4LMNAALDH1A1TSHR | |
| SCHEMBL21168227 | 0.90 | MAPT (0.62) | MAPTABCC4LMNAALDH1A1TSHR | |
| SCHEMBL16418484 | 0.90 | MAPT (0.62) | MAPTABCC4LMNAALDH1A1PPARG | |
| SCHEMBL4017942 | 0.89 | MAPT (0.50) | MAPTABCC4LMNAALDH1A1TSHR | |
| SCHEMBL17954029 | 0.88 | MAPT (0.59) | MAPTABCC4LMNAALDH1A1PPARG | |
| Undecylenic Acid SCHEMBL15263696 | 0.87 | MAPT (0.95) | MAPTABCC4LMNAALDH1A1TSHR | |
| SCHEMBL17950961 | 0.86 | MAPT (0.52) | MAPTABCC4LMNAALDH1A1TSHR | |
| SCHEMBL17955233 | 0.86 | MAPT (0.52) | MAPTABCC4LMNAALDH1A1TSHR | |
| SCHEMBL7576245 | 0.84 | MAPT (1.00) | MAPTABCC4LMNAALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3247405-B1 | SYNTHETIC APELIN FATTY ACID CONJUGATES WITH IMPROVED HALF-LIFE | NOVARTIS AG (CH) | 2019-07-17 | — | — | EP | disclosed |