Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | APAF1 | O14727 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | GALK1 | P51570 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17734623 | 0.92 | ESR2 (0.41) | ESR2ESR1MCL1PDE3BPDE3A | |
| SCHEMBL17734617 | 0.92 | ESR2 (0.41) | ESR2ESR1MCL1PDE3BPDE3A | |
| SCHEMBL17735242 | 0.88 | ESR2 (0.41) | ESR2ESR1MCL1PDE3BPDE3A | |
| SCHEMBL17734626 | 0.88 | ESR2 (0.38) | ESR2ESR1MAPTMEN1APAF1 | |
| SCHEMBL17733333 | 0.88 | ESR2 (0.38) | ESR2ESR1PDE3BPDE3AMAPT | |
| SCHEMBL17734603 | 0.88 | ESR2 (0.42) | ESR2ESR1MAPTL3MBTL1PSMB5 | |
| SCHEMBL15870794 | 0.87 | ESR2 (0.52) | ESR2MCL1PDE3BPDE3AMAPT | |
| SCHEMBL17199756 | 0.87 | ESR2 (0.52) | ESR2MCL1PDE3BPDE3AMAPT | |
| SCHEMBL19595343 | 0.85 | ESR2 (0.50) | ESR2MCL1PDE3BPDE3AMAPT | |
| SCHEMBL19651527 | 0.85 | ESR2 (0.50) | ESR2MCL1PDE3BPDE3AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3511316-A1 | ARYLDIAMINE COMPOUND AND ORGANIC ELECTROLUMINESCENT ELEMENT | Hodogaya Chemical Co., Ltd. (JP) | 2019-07-17 | — | — | EP | disclosed |