Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14707647 | 0.74 | — | — | |
| SCHEMBL737218 | 0.72 | — | — | |
| SCHEMBL25456226 | 0.68 | — | — | |
| SCHEMBL31332940 | 0.65 | IDO1 (0.30) | — | |
| SCHEMBL25042523 | 0.65 | — | — | |
| SCHEMBL31697688 | 0.63 | — | — | |
| SCHEMBL13222403 | 0.63 | PTGS1 (0.32) | PTGS1PTGS2 | |
| SCHEMBL17464658 | 0.63 | PTGS1 (0.32) | PTGS1PTGS2 | |
| SCHEMBL31332866 | 0.62 | — | — | |
| SCHEMBL22726078 | 0.62 | KDM5B (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10633354-B2 | Substituted tricyclic heterocyclic compounds | BRISTOL-MYERS SQUIBB COMPANY (US) | 2020-04-28 | — | — | US | disclosed |
| US-20190218193-A1 | SUBSTITUTED TRICYCLIC HETEROCYCLIC COMPOUNDS | BRISTOL MYERS SQUIBB CO (US) | 2019-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10633354-B2 | Substituted tricyclic heterocyclic compounds | S1PR1, S1PR3, S1PR2 | DHODH 1433/4885PTGS1 135/4885PTGS2 367/4885 |
| US-20190218193-A1 | SUBSTITUTED TRICYCLIC HETEROCYCLIC COMPOUNDS | S1PR1, S1PR3, S1PR2 | DHODH 1433/4885PTGS1 135/4885PTGS2 367/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.