Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 4/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.32 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.32 |
| ▸ | ADK | P55263 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29383125 | 1.00 | ADORA2A (0.34) | ADORA2AADORA3ADORA1ADORA2BADK | |
| SCHEMBL2983106 | 0.97 | ADORA2A (0.34) | ADORA2AADORA3ADORA1ADORA2BADK | |
| SCHEMBL7638539 | 0.84 | — | — | |
| SCHEMBL7035571 | 0.82 | PNP (0.31) | — | |
| SCHEMBL2117131 | 0.79 | PDPK1 (0.45) | ADORA2AADORA1ADK | |
| SCHEMBL2983115 | 0.76 | PDPK1 (0.45) | ADORA2AADORA1ADK | |
| Water SCHEMBL27761338 | 0.75 | PDPK1 (0.44) | ADORA2AADORA1ADK | |
| SCHEMBL5182595 | 0.74 | HIF1A (0.43) | ADORA2AADORA3ADORA1ADORA2B | |
| SCHEMBL240028 | 0.74 | HIF1A (0.43) | ADORA2AADORA3ADORA1ADORA2B | |
| SCHEMBL4436402 | 0.74 | HIF1A (0.43) | ADORA2AADORA3ADORA1ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130030007-A1 | Obesity Small Molecules | AKRON MOLECULES GMBH (AT) | 2013-01-31 | — | — | US | disclosed |
| EP-2521594-A2 | OBESITY SMALL MOLECULES | Akron Molecules GmbH (AT) | 2012-11-14 | — | — | EP | disclosed |
| US-20120094947-A1 | METHOD FOR THE SELECTIVE THERAPY OF DISEASE | LUBIN ADAM (US) | 2012-04-19 | — | — | US | disclosed |
| WO-2011083150-A2 | OBESITY SMALL MOLECULES | AKRON MOLECULES GMBH (AT) | 2011-07-14 | — | — | WO | disclosed |
| EP-2192905-A2 | METHOD FOR THE SELECTIVE THERAPY OF DISEASE | Lubin, Adam (US) | 2010-06-09 | — | — | EP | disclosed |
| WO-2009032057-A2 | METHOD FOR THE SELECTIVE THERAPY OF DISEASE | LUBIN ADAM (US) | 2009-03-12 | — | — | WO | disclosed |